Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50022502
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235904(N-(R)-sec-butyl-6-(4-(2-fluorophenyl)-1H-imidazol-...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235905(N-(S)-sec-butyl-6-(4-(2-fluorophenyl)-1H-imidazol-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235895(6-(5-amino-3-(2-fluorophenyl)-1H-pyrazol-4-yl)-N-(...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235907(6-(4-(2-fluorophenyl)-1H-imidazol-5-yl)-N-isopropy...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235907(6-(4-(2-fluorophenyl)-1H-imidazol-5-yl)-N-isopropy...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235896(6-(5-amino-3-(2-fluorophenyl)-1H-pyrazol-4-yl)-N-i...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235894(6-(5-amino-3-(2-fluorophenyl)-1H-pyrazol-4-yl)-N-(...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235899(6-(4-(2-fluorophenyl)oxazol-5-yl)-N-isopropylbenzo...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235901(N-(R)-sec-butyl-6-(4-(2-fluorophenyl)oxazol-5-yl)b...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235911(N-isopropyl-6-(4-phenyl-1H-imidazol-5-yl)benzo[d]t...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235893(N-(S)-sec-butyl-6-(4-(2-fluorophenyl)oxazol-5-yl)b...)
Affinity DataIC50: 10nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235900(6-(5-amino-3-(2-fluorophenyl)-1-methyl-1H-pyrazol-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235913(N-ethyl-6-(4-(2-fluorophenyl)oxazol-5-yl)benzo[d]t...)
Affinity DataIC50: 12nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235898(6-(4-(2-fluorophenyl)oxazol-5-yl)benzo[d]thiazol-2...)
Affinity DataIC50: 16nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235910(6-(5-amino-1-ethyl-3-(2-fluorophenyl)-1H-pyrazol-4...)
Affinity DataIC50: 17nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235908(6-(1-(2-fluorophenyl)-1H-pyrazol-5-yl)-N-isopropyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235916(N-isopropyl-6-(4-phenyloxazol-5-yl)benzo[d]thiazol...)
Affinity DataIC50: 21nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235914(N-isopropyl-6-(1-phenyl-1H-pyrazol-5-yl)benzo[d]th...)
Affinity DataIC50: 21nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235915(6-(1-(3-fluorophenyl)-1H-pyrazol-5-yl)-N-isopropyl...)
Affinity DataIC50: 33nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235891(N-isopropyl-6-(1-m-tolyl-1H-pyrazol-5-yl)benzo[d]t...)
Affinity DataIC50: 33nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235906(6-(4-(2-fluorophenyl)oxazol-5-yl)benzo[d]thiazole ...)
Affinity DataIC50: 47nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235912(6-(1-(4-fluorophenyl)-1H-pyrazol-5-yl)-N-isopropyl...)
Affinity DataIC50: 48nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235897(6-(1-(3-chlorophenyl)-1H-pyrazol-5-yl)-N-isopropyl...)
Affinity DataIC50: 72nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235903(N-isopropyl-6-(1-o-tolyl-1H-pyrazol-5-yl)benzo[d]t...)
Affinity DataIC50: 146nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235902(6-(1-(2-chlorophenyl)-1H-pyrazol-5-yl)-N-isopropyl...)
Affinity DataIC50: 175nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235909(N-isopropyl-6-(1-p-tolyl-1H-pyrazol-5-yl)benzo[d]t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235892(6-(1-(4-chlorophenyl)-1H-pyrazol-5-yl)-N-isopropyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed