Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50022468
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235550(1-(4-(5-((4-aminocyclohexylidene)methyl)pyrrolo[1,...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235540(2,6-difluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235548(N1-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrol...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235572(N-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235547(1-(4-(5-(((3R,4R)-4-amino-3-hydroxypiperidin-1-yl)...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235573(N1-(3-fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235556(1-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235565(2,5-difluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methy...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235567(1-(3-fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235575(N-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235558(5-chloro-2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235546(3-acetyl-N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpip...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235571(2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpip...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235543(2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpip...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235561(N1-(3-fluoro-4-(5-methyl-6-(2-morpholinoethoxy)pyr...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235563(N1-(4-(6-(2-(dimethylamino)ethoxy)-5-methylpyrrolo...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235545(1-(3-fluoro-4-(5-((piperidin-4-ylamino)methyl)pyrr...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235554(1-(4-(6-(2-(dimethylamino)ethoxy)-5-methylpyrrolo[...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235555(N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235553(1-(4-(5-((3-(aminomethyl)azetidin-1-yl)methyl)pyrr...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235559(N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235549((S)-1-(4-(5-((3-aminopyrrolidin-1-yl)methyl)pyrrol...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 200nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235564(1-(3-fluoro-4-(5-phenylpyrrolo[1,2-f][1,2,4]triazi...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235570(1-(3-fluoro-4-(5-(piperazin-1-ylmethyl)pyrrolo[1,2...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235562(1-(4-(5-((4-acetamidopiperidin-1-yl)methyl)pyrrolo...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235551((R)-1-(4-(5-((3-aminopyrrolidin-1-yl)methyl)pyrrol...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235552(2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-morpholinoet...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235568(2-fluoro-N-(3-fluoro-4-(5-methylpyrrolo[1,2-f][1,2...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235542(N1-(3-fluoro-4-(5-methylpyrrolo[1,2-f][1,2,4]triaz...)
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235541(1-(3-fluoro-4-(5-((4-methylpiperazin-1-yl)methyl)p...)
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235560(1-(3-fluoro-4-(5-((4-hydroxypiperidin-1-yl)methyl)...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235569(1-(3-fluoro-4-(5-(morpholinomethyl)pyrrolo[1,2-f][...)
Affinity DataIC50: 990nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235566(1-(4-(5-((4-(aminomethyl)piperidin-1-yl)methyl)pyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235557(1-(4-(5-((3-aminopropylamino)methyl)pyrrolo[1,2-f]...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235574(1-(4-(5-chloropyrrolo[1,2-f][1,2,4]triazin-4-yloxy...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of lckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of InsRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed