Compile Data Set for Download or QSAR
Report error Found 423 Enz. Inhib. hit(s) with all data for entry = 50038281
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3556(PD153035 Analog | 4-[(3-Bromophenyl)amino]-6,7-die...)
Affinity DataIC50: 0.00603nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3567(CHEMBL328106 | N-(4-bromophenyl)-6,7-dimethoxyquin...)
Affinity DataIC50: 0.0724nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122385(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122387(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122386(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3303(4-N-(3-bromophenyl)quinazoline-4,6,7-triamine | CH...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122390(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3302(4-[(3-bromophenyl)amino]quinazoline-6,7-diol | 44 ...)
Affinity DataIC50: 0.174nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3557(N-(3-bromophenyl)-6,7-dipropoxyquinazolin-4-amine ...)
Affinity DataIC50: 0.174nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122384(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piper...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM17060(CHEMBL319556 | 1-(2,6-dichlorophenyl)-5-(2,4-diflu...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3534(6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...)
Affinity DataIC50: 0.245nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027266(CHEMBL270696)
Affinity DataIC50: 0.245nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027338(CHEMBL53426)
Affinity DataIC50: 0.251nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027274(CHEMBL271122)
Affinity DataIC50: 0.282nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122391(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piper...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027273(CHEMBL272865)
Affinity DataIC50: 0.513nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122383(1-(2,6-Dichloro-phenyl)-5-(2,4-difluoro-phenyl)-7-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027310(CHEMBL408399)
Affinity DataIC50: 0.617nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3544(4-N-(3-bromophenyl)-7-N-methylquinazoline-4,6,7-tr...)
Affinity DataIC50: 0.692nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3684(8-N-(3-bromophenyl)-2-N-methyl-[1,3]diazino[5,4-d]...)
Affinity DataIC50: 0.776nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3688(4-[(3-Bromophenyl)amino]-6-[[2-(4-morpholino)ethyl...)
Affinity DataIC50: 0.813nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3533(CHEMBL1204305 | N-(3-iodophenyl)-6,7-dimethoxyquin...)
Affinity DataIC50: 0.891nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122407(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piper...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027318(CHEMBL272187)
Affinity DataIC50: 0.912nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027267(CHEMBL270695)
Affinity DataIC50: 0.933nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3685(4-[(3-Bromophenyl)amino]-6-(dimethylamino)pyrimido...)
Affinity DataIC50: 0.955nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50120101((2-Chloro-6-methyl-phenyl)-[8-(4-methyl-piperazin-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM17058(CHEMBL94556 | methyl 5-(2-chlorophenyl)-1-(2,6-dic...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122398(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027314(CHEMBL427832)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7692(4-{2-[(3Z)-4-(2-methylpropyl)-2-oxo-2,3-dihydro-1H...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027276(CHEMBL270895)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122378(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3683(6-Amino-4-[(3-bromophenyl)amino]pyrimido[5,4-d]pyr...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027270(CHEMBL405771)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7693(4-{2-[(3Z)-4-(2-methylprop-1-en-1-yl)-2-oxo-2,3-di...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50122401(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piper...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7746(4-({[(3Z)-4-oxo-5,10-diazatricyclo[7.4.0.0^{2,6}]t...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7745(4-[N -2-Oxo-2,3-dihydropyrrolo[3,2-f]quinolin-1-yl...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50120116(N*4*-(2-Chloro-6-methyl-phenyl)-N*7*-(2-dimethylam...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7727(3-{[4-(Aminosulfonyl)phenyl]hydrazono}-N-(2,6-dime...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50027309(CHEMBL271334)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7719(4-({[(3Z)-5-(3-methylbutanoyl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50120087(N-(2-chloro-6-methylphenyl)-8-(4-ethylpiperazin-1-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50120090(N4-(2-chloro-6-methylphenyl)-N8,N8-diethylimidazo[...)
Affinity DataIC50: 2nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7688(4-[1-(5-Oxazol-5-yl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50120094(N-(2-chloro-6-methylphenyl)-7,8-dimethoxyimidazo[1...)
Affinity DataIC50: 2nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50112911(N-(2-chloro-6-methylphenyl)-6,7-dimethoxyimidazo[1...)
Affinity DataIC50: 2nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
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