Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 2471
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21011(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-Bzl | (2S)-2-{...)
Affinity DatapH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21010(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-Bzl | (2S)-2-{[...)
Affinity DatapH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKd:  0.5nM EC50:  37nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataKd:  0.450nM EC50:  1.60nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21007([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  0.0460nM ΔG°:  -59.0kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21012(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-3,5-Bzl(CF3)2 |...)
Affinity DataKi:  0.610nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21010(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-Bzl | (2S)-2-{[...)
Affinity DataKi:  0.650nM ΔG°:  -52.4kJ/mole EC50:  0.710nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21016([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acet...)
Affinity DataKi:  0.730nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21013(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-3,5-Bzl(CF3)2 ...)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21011(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-Bzl | (2S)-2-{...)
Affinity DataKi:  1.60nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21007([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  1.60nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/mole EC50:  1.10nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21013(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-3,5-Bzl(CF3)2 ...)
Affinity DataKi:  6.10nM ΔG°:  -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21013(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-3,5-Bzl(CF3)2 ...)
Affinity DataKi:  6.80nM ΔG°:  -46.6kJ/mole EC50:  72nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21012(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-3,5-Bzl(CF3)2 |...)
Affinity DataKi:  9.5nM ΔG°:  -45.8kJ/mole EC50:  57nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21010(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-Bzl | (2S)-2-{[...)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/mole EC50:  17nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21010(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-Bzl | (2S)-2-{[...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21009(benzyl (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-...)
Affinity DataKi:  29nM ΔG°:  -43.0kJ/mole EC50:  36nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21009(benzyl (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-...)
Affinity DataKi:  31nM ΔG°:  -42.9kJ/mole EC50:  85nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21013(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-3,5-Bzl(CF3)2 ...)
Affinity DataKi:  31nM ΔG°:  -42.9kJ/mole EC50:  120nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21012(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-3,5-Bzl(CF3)2 |...)
Affinity DataKi:  33nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21011(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-Bzl | (2S)-2-{...)
Affinity DataKi:  46nM ΔG°:  -41.9kJ/mole EC50:  29nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21007([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/mole EC50:  35nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21012(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-3,5-Bzl(CF3)2 |...)
Affinity DataKi:  72nM ΔG°:  -40.8kJ/mole EC50:  80nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21011(H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NMe-Bzl | (2S)-2-{...)
Affinity DataKi:  77nM ΔG°:  -40.6kJ/mole EC50:  150nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21009(benzyl (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-...)
Affinity DataKi:  100nM ΔG°:  -40.0kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21016([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acet...)
Affinity DataKi:  130nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21007([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  180nM ΔG°:  -38.5kJ/mole EC50:  140nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21009(benzyl (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-...)
Affinity DataKi:  270nM ΔG°:  -37.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed