Compile Data Set for Download or QSAR
Report error Found 134 Enz. Inhib. hit(s) with all data for entry = 50038154
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372440(CHEMBL260957)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372442(CHEMBL260740)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372441(CHEMBL260958)
Affinity DataEC50:  2.50E+4nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372452(CHEMBL409847)
Affinity DataIC50: 1nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Mouse)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372470(CHEMBL403323)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372470(CHEMBL403323)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372451(CHEMBL270739)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50216027(N-hydroxy-6-(2-phenylacetamido)benzo[b]thiophene-2...)
Affinity DataIC50: 11.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372453(CHEMBL410636)
Affinity DataIC50: 13nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372446(CHEMBL272401)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372446(CHEMBL272401)
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372470(CHEMBL403323)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372456(CHEMBL271799)
Affinity DataIC50: 18nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372450(CHEMBL270740)
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372464(CHEMBL271798)
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372428(CHEMBL272615)
Affinity DataIC50: 26nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372449(CHEMBL406650)
Affinity DataIC50: 26.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50216032(N-hydroxy-5-(2-phenylacetamido)benzo[b]thiophene-2...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372427(CHEMBL279797)
Affinity DataIC50: 36nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372448(CHEMBL270893)
Affinity DataIC50: 36.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 37nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372462(CHEMBL270249)
Affinity DataIC50: 38nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Mouse)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50234054(N-hydroxy-6-(3,4-dihydro-4-oxo-6-phenyl-2-pyrimidi...)
Affinity DataIC50: 39nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Mouse)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50234055(N-hydroxy-5-(6-oxo-4-phenyl-1,6-dihydropyrimidin-2...)
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19423(N-[2-amino-5-(thiophen-2-yl)phenyl]-4-acetamidoben...)
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372429(CHEMBL272614)
Affinity DataIC50: 41nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372461(CHEMBL270887)
Affinity DataIC50: 41nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372457(CHEMBL260959 | US8648092, 45)
Affinity DataIC50: 45nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372430(CHEMBL261610)
Affinity DataIC50: 46.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372469(AZUMAMIDE E)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372432(CHEMBL429429)
Affinity DataIC50: 53nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372446(CHEMBL272401)
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372455(CHEMBL272403)
Affinity DataIC50: 55nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372446(CHEMBL272401)
Affinity DataIC50: 55nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372433(CHEMBL405504)
Affinity DataIC50: 76nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372435(CHEMBL270098)
Affinity DataIC50: 79nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372463(CHEMBL272402)
Affinity DataIC50: 79nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372469(AZUMAMIDE E)
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372461(CHEMBL270887)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19423(N-[2-amino-5-(thiophen-2-yl)phenyl]-4-acetamidoben...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372469(AZUMAMIDE E)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Mouse)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50234114(6-(4-benzyl-6-oxo-1,6-dihydropyrimidin-2-ylthio)-N...)
Affinity DataIC50: 103nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372436(CHEMBL259027)
Affinity DataIC50: 107nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Mouse)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 112nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Mouse)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372454(CHEMBL272024)
Affinity DataIC50: 121nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50372470(CHEMBL403323)
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
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