Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 2693
LigandPNGBDBM23489((1R,2S)-2-N-hydroxy-1-N,1-N-dimethyl-1-({4-[(2-met...)
Affinity DataKi:  1nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi:  3nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23477((1R,2R)-2-N-hydroxy-1-{3-[(2-methylquinolin-4-yl)m...)
Affinity DataKi:  5nM ΔG°:  -46.9kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23458(propan-2-yl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(2-...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23484(CHEMBL410462 | methyl (1R,2S)-2-(hydroxycarbamoyl)...)
Affinity DataKi:  8nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23482((1R,2R)-1-N-cyclohexyl-2-N-hydroxy-1-{3-[(2-methyl...)
Affinity DataKi:  9nM ΔG°:  -45.5kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23456(methyl (1R,2R)-1-{3-[(3,4-dichlorophenyl)methoxy]p...)
Affinity DataKi:  11nM ΔG°:  -45.0kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23480((1R,2R)-2-N-hydroxy-1-{3-[(2-methylquinolin-4-yl)m...)
Affinity DataKi:  11nM ΔG°:  -45.0kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23454(CHEMBL270558 | methyl (1R,2R)-2-(hydroxycarbamoyl)...)
Affinity DataKi:  12nM ΔG°:  -44.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23488((1R,2S)-2-N-hydroxy-1-N-methyl-1-({4-[(2-methylqui...)
Affinity DataKi:  14nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23476(ethyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(2-methyl...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23464(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-{[4-(trif...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23465(methyl (1R,2R)-1-{3-[(4-chlorophenyl)methoxy]pheny...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23470(methyl (1R,2R)-1-[3-(2-{3-[(1Z)-buta-1,3-dien-1-yl...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23469(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[2-(napht...)
Affinity DataKi:  60nM ΔG°:  -40.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23463(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-{[3-(trif...)
Affinity DataKi:  70nM ΔG°:  -40.4kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23471(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(naphthal...)
Affinity DataKi:  70nM ΔG°:  -40.4kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23497((1R,2S)-1-{[4-(but-2-yn-1-yloxy)phenyl]methyl}-2-N...)
Affinity DataKi:  80nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23466(methyl (1R,2R)-1-{3-[(3-fluorophenyl)methoxy]pheny...)
Affinity DataKi:  80nM ΔG°:  -40.1kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23478((1R,2R)-2-N-hydroxy-1-N-methyl-1-{3-[(2-methylquin...)
Affinity DataKi:  100nM ΔG°:  -39.6kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23462(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(3-metho...)
Affinity DataKi:  110nM ΔG°:  -39.3kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23490(methyl (1R,2S)-1-({4-[(3,4-dichlorophenyl)methoxy]...)
Affinity DataKi:  130nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23473(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(4-methyl...)
Affinity DataKi:  140nM ΔG°:  -38.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23459((1R,2R)-1-N-benzyl-2-N-hydroxy-1-{3-[(2-methylquin...)
Affinity DataKi:  140nM ΔG°:  -38.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23452(methyl (1S,2S)-1-[3-(benzyloxy)phenyl]-2-(hydroxyc...)
Affinity DataKi:  190nM ΔG°:  -38.0kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23472(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(2-methyl...)
Affinity DataKi:  240nM ΔG°:  -37.4kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23491(methyl (1R,2S)-1-({4-[(2-chlorophenyl)methoxy]phen...)
Affinity DataKi:  260nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23468(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(2-phenyl...)
Affinity DataKi:  290nM ΔG°:  -36.9kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23486((1R,2S)-1-{[4-(benzyloxy)phenyl]methyl}-2-N-hydrox...)
Affinity DataKi:  360nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23496(methyl (1R,2S)-1-{[4-(but-2-yn-1-yloxy)phenyl]meth...)
Affinity DataKi:  420nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23455((1R,2R)-1-N-hydroxy-2-{3-[(2-methylquinolin-4-yl)m...)
Affinity DataKi:  700nM ΔG°:  -34.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23485(methyl (1R,2S)-1-{[4-(benzyloxy)phenyl]methyl}-2-(...)
Affinity DataKi:  800nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23475(methyl (1R,2R)-1-[3-(cyclohexylmethoxy)phenyl]-2-(...)
Affinity DataKi:  900nM ΔG°:  -34.2kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23457(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-phenoxyph...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23460((1R,2R)-1-[3-(benzyloxy)phenyl]-2-N-hydroxycyclopr...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23474(methyl (1R,2R)-1-[3-(but-2-yn-1-yloxy)phenyl]-2-(h...)
Affinity DataKi:  1.60E+3nM ΔG°:  -32.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23479((1R,2R)-2-N-hydroxy-1-N,1-N-dimethyl-1-{3-[(2-meth...)
Affinity DataKi:  2.70E+3nM ΔG°:  -31.5kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23461(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-methoxyph...)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.2kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23481((1R,2R)-1-N-benzyl-2-N-hydroxy-1-N-methyl-1-{3-[(2...)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.2kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23467(methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(naphthal...)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.2kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23494(ethyl (1R,2S)-2-(hydroxycarbamoyl)-1-[(4-phenoxyph...)
Affinity DataKi:  3.10E+3nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23483((1R,2R)-N-hydroxy-2-[(4-methylpiperazin-1-yl)carbo...)
Affinity DataKi:  5.00E+3nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23495(methyl (1R,2S)-1-{[4-(cyclohexylmethoxy)phenyl]met...)
Affinity DataKi:  2.60E+4nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23492(methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[2-(naph...)
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed
LigandPNGBDBM23493(methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[2-(naph...)
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2008
Entry Details Article
PubMed