Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50038600
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50377933(CHEMBL1744354)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242595(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242577(6-{[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242517((2S,4S)-1-(N-Cyclopentylglycyl)-4-fluoropyrrolidin...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242576((2S,4S)-1-(N-{2-[(5-Chloropyridin-2-yl)amino]ethyl...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242575((2S,4S)-4-Fluoro-1-{N-[2-(pyridin-2-ylamino)ethyl]...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242495((2S,4S)-1-[N-(tert-Butyl)glycyl]-4-fluoropyrrolidi...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242593(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242530((2S,4S)-1-(N-2-Adamantylglycyl)-4-fluoropyrrolidin...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242516((2S,4S)-1-(N-Cyclobutylglycyl)-4-fluoropyrrolidine...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242531((2S,4S)-4-Fluoro-1-[N-(3-hydroxy-1-adamantyl)-glyc...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242519((2S,4S)-1-(N-Cyclooctylglycyl)-4-fluoropyrrolidine...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242518((2S,4S)-4-Fluoro-1-{N-[1-(hydroxymethyl)cyclopenty...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242529((2S,4S)-1-(N-1-Adamantylglycyl)-4-fluoropyrrolidin...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242579(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242513((2S,4S)-4-Fluoro-1-[N-(2-hydroxy-1,1-dimethylethyl...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242533((2S,4S)-4-Fluoro-1-[N-(5-hydroxy-2-adamantyl)-glyc...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242580(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242594(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242596(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242476(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11113(NVP-DPP728 | cyanopyrrolidine derivative 2 | CHEMB...)
Affinity DataIC50: 7nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242475(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242496((2S,4S)-4-Fluoro-1-(N-isopropylglycyl)pyrrolidine-...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242578(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242532((2S,4S)-4-Fluoro-1-[N-(3-methoxy-1-adamantyl)-glyc...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242478((2S,4S)-4-Fluoro-1-{N-[1-(2-furyl)-1-methylethyl]-...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242497((2S,4S)-4-Fluoro-1-[N-(3-isopropoxypropyl)glycyl]p...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242491((2S,4S)-4-Fluoro-1-{N-[1-methyl-1-(2-thienyl)-ethy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242597(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 13nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50377932(CHEMBL1203962)
Affinity DataIC50: 13nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242493((2S,4S)-1-{N-[(2E)-1,1-Dimethyl-3-phenylprop-2-en-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242477((2S,4S)-4-Fluoro-1-[N-(1-methyl-1-pyridin-2-ylethy...)
Affinity DataIC50: 22nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242494((2S,4S)-1-{N-[2-(3,4-Dimethoxyphenyl)ethyl]glycyl}...)
Affinity DataIC50: 27nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242610(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 31nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242515((2S,4S)-1-(N-Cyclopropylglycyl)-4-fluoropyrrolidin...)
Affinity DataIC50: 33nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242612((2S,4S)-4-Fluoro-1-(N-{2-[(4-cyanobenzyl)amino]-1,...)
Affinity DataIC50: 39nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242609(N-[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]...)
Affinity DataIC50: 75nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242492((2S,4S)-1-{N-[1-(1-Benzofuran-2-yl)-1-methylethyl]...)
Affinity DataIC50: 88nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242608(2,2-Bis(4-chlorophenyl)-N-[2-({2-[(2S,4S)-2-cyano-...)
Affinity DataIC50: 109nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242474((2S,4S)-1-{N-[2-(Diethylamino)-1,1-dimethylethyl]g...)
Affinity DataIC50: 252nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242611((S,4S)-4-Fluoro-1-{N-[2-(isobutylamino)-1,1-dimeth...)
Affinity DataIC50: 316nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242514((2S,4S)-1-[N-(1,1-Diethylprop-2-yn-1-yl)glycyl]-4-...)
Affinity DataIC50: 316nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed