Compile Data Set for Download or QSAR
Report error Found 364 Enz. Inhib. hit(s) with all data for entry = 50038291
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328697((R)-5-guanidino-N-(2-((S)-5-guanidino-1-oxo-1-(thi...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374336(CHEMBL404268)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125042(2-((R)-3-benzyl-4-(benzylsulfonyl)-2-oxopiperazin-...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072741((6S,8aS)-N-((S)-1-(1-carbamimidoylpiperidin-4-yl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374334(CHEMBL257933)
Affinity DataIC50: 1nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374329(CHEMBL256427)
Affinity DataIC50: 1nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374312(CHEMBL270834)
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374313(CHEMBL271047)
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328701((S)-2-(4-(4-chlorophenylsulfonyl)-2-oxopiperazin-1...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374337(CHEMBL401963)
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374359(CHEMBL404058)
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374361(CHEMBL429253)
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin K(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50148291(((S)-1-Formyl-pentyl)-carbamic acid (S)-2-cyclohex...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328702((S)-N-(5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374281(CHEMBL271495)
Affinity DataIC50: 3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125019(2-((S)-4-(benzylsulfonyl)-3-(3-guanidinopropyl)-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374389(CHEMBL411500)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374331(CHEMBL258105)
Affinity DataIC50: 4nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374388(CHEMBL256268)
Affinity DataIC50: 4nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072740((S)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374385(CHEMBL255409)
Affinity DataIC50: 5nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374386(CHEMBL269970)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374387(CHEMBL257928)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374338(CHEMBL403629)
Affinity DataIC50: 6nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM12972((2S)-2-[(2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carb...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374368(CHEMBL256191)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374287(CHEMBL402616)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374282(CHEMBL271936)
Affinity DataIC50: 8nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328702((S)-N-(5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374358(CHEMBL258296)
Affinity DataIC50: 8nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50228756(((R)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-b...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374289(CHEMBL269822)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374288(CHEMBL272798)
Affinity DataIC50: 9nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374398(CHEMBL269969)
Affinity DataIC50: 10nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM12972((2S)-2-[(2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carb...)
Affinity DataIC50: 10nMAssay Description:Inhibition of kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125038(2-[(S)-3-(3-Guanidino-propyl)-2-oxo-piperazin-1-yl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374312(CHEMBL270834)
Affinity DataIC50: 13nMAssay Description:Inhibition of kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374391(CHEMBL271255)
Affinity DataIC50: 13nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125030(2-[(R)-3-(3-Guanidino-propyl)-2-oxo-4-phenylmethan...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328697((R)-5-guanidino-N-(2-((S)-5-guanidino-1-oxo-1-(thi...)
Affinity DataIC50: 14nMAssay Description:Inhibition of kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374339(CHEMBL258104)
Affinity DataIC50: 17nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374342(CHEMBL404534)
Affinity DataIC50: 21nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374360(CHEMBL412057)
Affinity DataIC50: 28nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374312(CHEMBL270834)
Affinity DataIC50: 29nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50374313(CHEMBL271047)
Affinity DataIC50: 29nMAssay Description:Inhibition of kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 364 total ) | Next | Last >>
Jump to: