Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50021842
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228403(8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-m...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228394((R)-2-(2-(2-(8-(3-aminopiperidin-1-yl)-7-(but-2-yn...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228392((S)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylm...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228406((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228397(CHEMBL237067 (9) | CHEMBL237067 | 8-((S)-3-amino-p...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228398(8-((R)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-meth...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228391((R)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylm...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50151006(8-(3-Amino-piperidin-1-yl)-3-methyl-7-(3-methyl-bu...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228391((R)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylm...)
Affinity DataIC50: 5nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228393((R)-1-(4-methoxybenzyl)-8-(3-aminopiperidin-1-yl)-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228399(8-((S)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-meth...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 25nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228392((S)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylm...)
Affinity DataIC50: 26nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228396(8-(3-aminopiperidin-1-yl)-1,3-dimethyl-7-(3-methyl...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228397(CHEMBL237067 (9) | CHEMBL237067 | 8-((S)-3-amino-p...)
Affinity DataIC50: 50nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228404(8-(3-aminopiperidin-1-yl)-3-methyl-7-(3-methylbut-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228409(8-(3-aminopiperidin-1-yl)-7-benzyl-1,3-dimethyl-1H...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228400(8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-1,3-dimet...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228405(7-(but-2-ynyl)-1,3-dimethyl-8-(piperazin-1-yl)-1H-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228395(8-(3-aminopiperidin-1-yl)-1-benzyl-3-methyl-7-(3-m...)
Affinity DataIC50: 284nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228403(8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-m...)
Affinity DataIC50: 295nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228406((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)
Affinity DataIC50: 430nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228393((R)-1-(4-methoxybenzyl)-8-(3-aminopiperidin-1-yl)-...)
Affinity DataIC50: 518nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228402(1,3-dimethyl-7-(3-methylbut-2-enyl)-8-(piperazin-1...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228399(8-((S)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-meth...)
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228394((R)-2-(2-(2-(8-(3-aminopiperidin-1-yl)-7-(but-2-yn...)
Affinity DataIC50: 1.17E+3nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228401(7-benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228408(7-benzyl-3-methyl-8-(piperazin-1-yl)-1H-purine-2,6...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228398(8-((R)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-meth...)
Affinity DataIC50: 6.16E+3nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed