Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50021722
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227174((S)-tetrahydro-2H-pyran-4-yl 1-(5-(2-(1H-indol-3-y...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227175((R)-tetrahydro-2H-pyran-4-yl 1-(5-(2-(1H-indol-3-y...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227171((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227180((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227177((R)-pyridin-2-yl 1-(5-(2-(1H-indol-3-yl)ethyl)-4-(...)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227167((S)-N-((R)-1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-meth...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227172((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227169((S)-N-((S)-1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-meth...)
Affinity DataEC50:  440nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227166((S)-pyridin-2-yl 1-(5-(2-(1H-indol-3-yl)ethyl)-4-(...)
Affinity DataEC50:  1.58E+3nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227177((R)-pyridin-2-yl 1-(5-(2-(1H-indol-3-yl)ethyl)-4-(...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM19294(CHEMBL374643 | 2-amino-N-[(1R)-2-(1H-indol-3-yl)-1...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227171((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227180((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227167((S)-N-((R)-1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-meth...)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208662((R)-N-(1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208678((R)-N-(1-(4-(4-methoxybenzyl)-5-(3-phenylpropyl)-4...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227175((R)-tetrahydro-2H-pyran-4-yl 1-(5-(2-(1H-indol-3-y...)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208653((R)-N-(1-(4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1...)
Affinity DataIC50: 62nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227181((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(2,4-dimeth...)
Affinity DataIC50: 83nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208688((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(2,4-dimeth...)
Affinity DataIC50: 108nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208665((R)-N-(1-(4-(4-methoxybenzyl)-5-benzyl-4H-1,2,4-tr...)
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227183((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227166((S)-pyridin-2-yl 1-(5-(2-(1H-indol-3-yl)ethyl)-4-(...)
Affinity DataIC50: 175nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM19294(CHEMBL374643 | 2-amino-N-[(1R)-2-(1H-indol-3-yl)-1...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227173((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208662((R)-N-(1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4...)
Affinity DataIC50: 275nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227178((S)-N-(1-(4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1...)
Affinity DataIC50: 450nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227182((R)-benzyl 3-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-meth...)
Affinity DataIC50: 450nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208645((R)-N-(1-(4-(2,4-dimethoxybenzyl)-5-benzyl-4H-1,2,...)
Affinity DataIC50: 560nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208678((R)-N-(1-(4-(4-methoxybenzyl)-5-(3-phenylpropyl)-4...)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208688((R)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(2,4-dimeth...)
Affinity DataIC50: 620nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227169((S)-N-((S)-1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-meth...)
Affinity DataIC50: 650nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227179((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataIC50: 800nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208653((R)-N-(1-(4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1...)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227172((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxyb...)
Affinity DataIC50: 820nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50208665((R)-N-(1-(4-(4-methoxybenzyl)-5-benzyl-4H-1,2,4-tr...)
Affinity DataIC50: 870nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227170((S)-N-(1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227164((S)-N-(1-(4-(4-methoxybenzyl)-5-(3-phenylpropyl)-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227165((S)-N-(1-(4-(2,4-dimethoxybenzyl)-5-benzyl-4H-1,2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227168((S)-N-(1-(4-(4-methoxybenzyl)-5-benzyl-4H-1,2,4-tr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227176((R)-N-(1-(4-(4-methoxybenzyl)-5-benzyl-4H-1,2,4-tr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227174((S)-tetrahydro-2H-pyran-4-yl 1-(5-(2-(1H-indol-3-y...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50227181((S)-N-(1-(5-(2-(1H-indol-3-yl)ethyl)-4-(2,4-dimeth...)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed