Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50021715
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227111(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)benz...)
Affinity DataIC50: 740nMAssay Description:Antagonist activity at human SST5R expressed in CHO cells assessed as reversal of somatostatin-14 induced cAMP responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227099(2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227100(2-(1-(4-chloro-3-ethoxybenzyl)piperidin-4-ylamino)...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227119(benzooxazol-2-yl-[1-(3-isobutoxy-4-methoxy-benzyl)...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227117(N-(1-(3-ethoxy-4-methylbenzyl)piperidin-4-yl)benzo...)
Affinity DataKi:  37nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227106(4-((4-(benzo[d]oxazol-2-ylamino)piperidin-1-yl)met...)
Affinity DataKi:  66nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227109(N-(1-(3-(cyclopentyloxy)-4-methoxybenzyl)piperidin...)
Affinity DataKi:  83nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227112(N-(1-(4-chloro-3-ethoxybenzyl)piperidin-4-yl)benzo...)
Affinity DataKi:  113nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227111(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)benz...)
Affinity DataKi:  121nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227116(4-((4-(benzo[d]thiazol-2-ylamino)piperidin-1-yl)me...)
Affinity DataKi:  149nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227107(2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...)
Affinity DataKi:  185nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227114(N-(1-(3-ethoxy-4-fluorobenzyl)piperidin-4-yl)benzo...)
Affinity DataKi:  194nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227105(N-(1-(4-methoxy-3-propoxybenzyl)piperidin-4-yl)ben...)
Affinity DataKi:  293nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227103(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)benz...)
Affinity DataKi:  326nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227115(N-(1-(3-ethoxy-4-(trifluoromethoxy)benzyl)piperidi...)
Affinity DataKi:  524nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227111(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)benz...)
Affinity DataKi:  624nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227125(N-(1-((1,4-dimethoxynaphthalen-2-yl)methyl)piperid...)
Affinity DataKi:  683nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227120(N-(1-((1,4-dimethoxynaphthalen-2-yl)methyl)piperid...)
Affinity DataKi:  794nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227124(1-(4-fluorobenzyl)-N-(1-((1,4-dimethoxynaphthalen-...)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227127(1-(4-fluorobenzyl)-N-(1-((7-methyl-1H-indol-3-yl)m...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227110(1-(4-fluorobenzyl)-N-(1-((2,3-dihydrobenzofuran-5-...)
Affinity DataKi:  1.63E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227121(N-(1-(3,4-dimethoxybenzyl)piperidin-4-yl)benzo[d]t...)
Affinity DataKi:  1.79E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227101(N-(1-((1H-indol-5-yl)methyl)piperidin-4-yl)-1-(4-f...)
Affinity DataKi:  3.95E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227104(1-(4-fluorobenzyl)-N-(1-(4-methoxybenzyl)piperidin...)
Affinity DataKi:  3.95E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM24226(cid_2247 | [3H]-ASTEMIZOLE | Hismanal | ASTEMIZOLE...)
Affinity DataKi:  4.07E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227122([1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-(1-phe...)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227126(4-((4-(benzo[d]thiazol-2-ylamino)piperidin-1-yl)me...)
Affinity DataKi:  5.13E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227102(1-(4-fluorobenzyl)-N-(1-benzylpiperidin-4-yl)-1H-b...)
Affinity DataKi:  6.12E+3nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227113(1-(4-fluorobenzyl)-N-(1-((1,2,3,4-tetrahydronaphth...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227099(2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human SST1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227099(2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human SST2RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227099(2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human SST3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227118(1-(4-fluorobenzyl)-N-(1-(4-fluorophenethyl)piperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227108(N-(1-(4-(trifluoromethoxy)phenethyl)piperidin-4-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227123(1-(4-fluorobenzyl)-N-(1-(3-phenylpropyl)piperidin-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50227099(2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human SST4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed