Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50042285
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 18nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003351(CHEMBL101054 | 5-(4-Butoxy-[1,2,5]thiadiazol-3-yl)...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 29nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003366(CHEMBL75552 | CHEMBL327754 | 1-methyl-5-(4-(pentyl...)
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50072215(3-(3-((4-phenylbutyl)oxy)-1,2,5-thiadiazol-4-yl)-1...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 52nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423615(CHEMBL405125)
Affinity DataIC50: 59nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 81nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003365(3-(3-(ethoxy)-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetra...)
Affinity DataIC50: 141nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50072234(1-Methyl-5-[4-(4-phenyl-butoxy)-[1,2,5]thiadiazol-...)
Affinity DataIC50: 145nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423611(CHEMBL270031)
Affinity DataIC50: 162nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423607(CHEMBL408822)
Affinity DataIC50: 219nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423607(CHEMBL408822)
Affinity DataIC50: 275nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423614(CHEMBL403829)
Affinity DataIC50: 309nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423607(CHEMBL408822)
Affinity DataIC50: 407nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423613(CHEMBL271774)
Affinity DataIC50: 617nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423609(CHEMBL406802)
Affinity DataIC50: 646nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423608(CHEMBL272468)
Affinity DataIC50: 871nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423608(CHEMBL272468)
Affinity DataIC50: 871nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 955nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423612(CHEMBL406570)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423619(CHEMBL257683)
Affinity DataIC50: 1.07E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423610(CHEMBL255791)
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50072215(3-(3-((4-phenylbutyl)oxy)-1,2,5-thiadiazol-4-yl)-1...)
Affinity DataIC50: 2.14E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423608(CHEMBL272468)
Affinity DataIC50: 2.29E+3nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 2.40E+3nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423618(CHEMBL401694)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423609(CHEMBL406802)
Affinity DataIC50: 3.98E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423616(CHEMBL272359)
Affinity DataIC50: 7.08E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003366(CHEMBL75552 | CHEMBL327754 | 1-methyl-5-(4-(pentyl...)
Affinity DataIC50: 8.51E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50072234(1-Methyl-5-[4-(4-phenyl-butoxy)-[1,2,5]thiadiazol-...)
Affinity DataIC50: 9.12E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423607(CHEMBL408822)
Affinity DataIC50: 1.20E+4nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423611(CHEMBL270031)
Affinity DataIC50: 1.48E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423607(CHEMBL408822)
Affinity DataIC50: 2.88E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423607(CHEMBL408822)
Affinity DataIC50: 3.98E+4nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423610(CHEMBL255791)
Affinity DataIC50: 4.47E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423608(CHEMBL272468)
Affinity DataIC50: 5.25E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423608(CHEMBL272468)
Affinity DataIC50: 5.37E+4nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423617(CHEMBL255793)
Affinity DataIC50: 7.76E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003351(CHEMBL101054 | 5-(4-Butoxy-[1,2,5]thiadiazol-3-yl)...)
Affinity DataIC50: 7.76E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50423612(CHEMBL406570)
Affinity DataIC50: 1.10E+5nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed