Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50021488
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225216(2-(2,4-dichlorophenoxy)-5-(hydroxymethyl)phenol | ...)
Affinity DataKd:  0.300nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225229(2-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol | CHEMBL...)
Affinity DataKd:  42nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225221(2,3,6-trichloro-N-(4H-1,2,4-triazol-3-yl)benzamide...)
Affinity DataKd:  120nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225217(5-(chloromethyl)-2-(2,4-dichlorophenoxy)phenol | C...)
Affinity DataKd:  5.70nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225228(3-hydroxy-4-phenoxybenzoic acid | CHEMBL241454)
Affinity DataKd:  27nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225226(4-(2,4-dichlorophenoxy)-3-methoxybenzoic acid | CH...)
Affinity DataKd:  0.200nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225224(4-(2,4-dichlorophenoxy)-3-hydroxybenzaldehyde | CH...)
Affinity DataKd:  13.9nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataKd:  1.44E+5nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM25406(4-(2,4-dichlorophenoxy)-3-hydroxybenzoic acid | CH...)
Affinity DataKd:  27nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225219(3-methoxy-4-phenoxybenzaldehyde | CHEMBL241453)
Affinity DataKd:  88nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225226(4-(2,4-dichlorophenoxy)-3-methoxybenzoic acid | CH...)
Affinity DataIC50: 475nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225224(4-(2,4-dichlorophenoxy)-3-hydroxybenzaldehyde | CH...)
Affinity DataIC50: 520nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225217(5-(chloromethyl)-2-(2,4-dichlorophenoxy)phenol | C...)
Affinity DataIC50: 850nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225221(2,3,6-trichloro-N-(4H-1,2,4-triazol-3-yl)benzamide...)
Affinity DataIC50: 1.06E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225219(3-methoxy-4-phenoxybenzaldehyde | CHEMBL241453)
Affinity DataIC50: 1.31E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225216(2-(2,4-dichlorophenoxy)-5-(hydroxymethyl)phenol | ...)
Affinity DataIC50: 1.36E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225218(4-(chloromethyl)-2-methoxy-1-phenoxybenzene | CHEM...)
Affinity DataIC50: 1.94E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM25406(4-(2,4-dichlorophenoxy)-3-hydroxybenzoic acid | CH...)
Affinity DataIC50: 2.59E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225229(2-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol | CHEMBL...)
Affinity DataIC50: 3.10E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225227(2,4-dichloro-1-(4-(chloromethyl)-2-methoxyphenoxy)...)
Affinity DataIC50: 3.16E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225228(3-hydroxy-4-phenoxybenzoic acid | CHEMBL241454)
Affinity DataIC50: 3.18E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225220(D-thyroxine | O-(4-hydroxy-3,5-diiodophenyl)-3,5-d...)
Affinity DataIC50: 7.17E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225230(4-(2,4-dinitrophenoxy)-3-methoxybenzoic acid | CHE...)
Affinity DataIC50: 2.00E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225222((4-(2,4-dinitrophenoxy)-3-methoxyphenyl)methanol |...)
Affinity DataIC50: 2.00E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225231(3-methoxy-4-phenoxybenzoic acid | CHEMBL392872)
Affinity DataIC50: 4.10E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225225(5-(hydroxymethyl)-2-phenoxyphenol | CHEMBL238590)
Affinity DataIC50: 4.50E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataIC50: 5.35E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
Institute of Sciences

Curated by ChEMBL
LigandPNGBDBM50225223(4-(2,4-dinitrophenoxy)-3-hydroxybenzaldehyde | CHE...)
Affinity DataIC50: 5.50E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed