Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 3558
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 0.180nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 0.200nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 0.230nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 0.300nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 0.310nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 0.350nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 0.450nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 0.460nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 0.590nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 0.720nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 0.830nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 1nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 3.30nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 6.90nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataIC50: 8.70nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 22nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 36nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 36nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 87.3nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 162nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 675nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 903nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [D130V](Human)
Glaxosmithkline

LigandPNGBDBM50220156((R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-ox...)
Affinity DataIC50: 1.19E+3nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataIC50: 2.09E+3nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataKi:  1.70nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [A356T](Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataKi:  66nMpH: 6.8Assay Description:wild-type HCT116 selected at 6WT-6x the IC95More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11 [A356T](Human)
Glaxosmithkline

LigandPNGBDBM36350(CID12000936 | 6-[4-(Trifluoromethyl)phenyl]-3,4-di...)
Affinity DataKi:  109nMpH: 6.8Assay Description:wild-type HCT116 selected at 3 the IC95More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed