Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50021323
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM34143(CHEMBL175835 | E-6837)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223292(N-(4-chlorobenzyl)-2-nitro-5-(piperazin-1-yl)benze...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223281(5-(4-methylpiperazin-1-yl)-2-nitro-N-(1-phenylethy...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223306(N-(2-(2-methoxyphenoxy)ethyl)-5-(4-methylpiperazin...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223288(N-(furan-2-ylmethyl)-2-nitro-5-(piperazin-1-yl)ben...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223309(5-(4-methylpiperazin-1-yl)-2-nitro-N-(2-(o-tolylox...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223303(1-methyl-4-(4-nitro-3-phenoxyphenyl)piperazine | C...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223294(N-benzyl-2-nitro-5-(piperazin-1-yl)benzenamine | C...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223304(2-nitro-N-phenethyl-5-(piperazin-1-yl)benzenamine ...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223277(2-(benzylamino)-4-(4-methylpiperazin-1-yl)benzonit...)
Affinity DataKi:  47nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223293(N-(4-chlorobenzyl)-5-(4-methylpiperazin-1-yl)-2-ni...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223305(N-(furan-2-ylmethyl)-5-(4-methylpiperazin-1-yl)-2-...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223290(N-(2-(4-tert-butylphenoxy)ethyl)-5-(4-methylpipera...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223277(2-(benzylamino)-4-(4-methylpiperazin-1-yl)benzonit...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223297(2-nitro-N-(2-phenoxyethyl)-5-(piperazin-1-yl)benze...)
Affinity DataKi:  114nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223285(5-(4-methylpiperazin-1-yl)-2-nitro-N-phenethylbenz...)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223279(2-nitro-5-(piperazin-1-yl)-N-(2-(o-tolyloxy)ethyl)...)
Affinity DataKi:  163nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223283(N-(2-amino-4-(4-methylpiperazin-1-yl)phenyl)-N-ben...)
Affinity DataKi:  164nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223278(N-(4-fluorobenzyl)-5-(4-methylpiperazin-1-yl)-2-ni...)
Affinity DataKi:  172nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223302(N-(2-(4-methoxyphenoxy)ethyl)-5-(4-methylpiperazin...)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223298(1-(3-(3,5-dimethyl-1H-pyrazol-1-yl)-4-nitrophenyl)...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223284(N-(2-(4-chlorophenoxy)ethyl)-2-nitro-5-(piperazin-...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223311(2-(benzyloxy)-N-(furan-2-ylmethyl)-5-(4-methylpipe...)
Affinity DataKi:  402nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223310(N-benzyl-2-methoxy-5-(4-methylpiperazin-1-yl)benze...)
Affinity DataKi:  409nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223286(methyl 4-(4-methylpiperazin-1-yl)-2-(phenethylamin...)
Affinity DataKi:  462nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223299(N-(5-(4-methylpiperazin-1-yl)-2-nitrophenyl)-1H-py...)
Affinity DataKi:  481nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223301(1-(3-(3,5-dimethyl-1H-pyrazol-1-yl)-4-nitrophenyl)...)
Affinity DataKi:  482nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223295(N-benzyl-2-(benzyloxy)-5-(4-methylpiperazin-1-yl)b...)
Affinity DataKi:  928nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223289(2-methoxy-5-(4-methylpiperazin-1-yl)-N-phenethylbe...)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223307(2-(5-(4-methylpiperazin-1-yl)-2-nitrophenyl)-4-phe...)
Affinity DataKi:  1.22E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223291(5-(4-methylpiperazin-1-yl)-2-nitro-N-(pyridin-3-yl...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223280(2-(benzyloxy)-5-(4-methylpiperazin-1-yl)-N-pheneth...)
Affinity DataKi:  1.28E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223300(2-(furan-2-ylmethylamino)-4-(4-methylpiperazin-1-y...)
Affinity DataKi:  1.37E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223296(N1-(2-aminoethyl)-N3-benzyl-4-nitrobenzene-1,3-dia...)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223282(2-nitro-5-(piperazin-1-yl)-N-(pyridin-3-ylmethyl)b...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223287(methyl 2-(benzylamino)-5-(4-methylpiperazin-1-yl)b...)
Affinity DataKi:  1.89E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataKi:  4.49E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed