Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50021301
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223074(N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(6-chlo...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223067(N-(6-amino-2-methyl-pyridin-3-ylmethyl)-2-{6-chlor...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223066(N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-(6-c...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223081(N-[2-(carbamimidamidooxy)ethyl]-2-(6-chloro-3-{[2,...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223071(N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(6-chlo...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223069(N-[2-(carbamimidamidooxy)ethyl]-2-(6-chloro-3-{[2,...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223078(N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)-2-(6-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223065(N-[2-(carbamimidamidooxy)ethyl]-2-(6-chloro-3-{[2,...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223075(N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-c...)
Affinity DataKi:  8.60nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223076(N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(6-chlo...)
Affinity DataKi:  10nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223077(N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-c...)
Affinity DataKi:  34nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223072(N-[2-(carbamimidamidooxy)ethyl]-2-{6-chloro-3-[(2,...)
Affinity DataKi:  47nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223073(N-[2-(carbamimidamidooxy)ethyl]-2-[6-chloro-2-fluo...)
Affinity DataKi:  57nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223068(N-[2-(carbamimidamidooxy)ethyl]-2-(6-chloro-2-fluo...)
Affinity DataKi:  58nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223064(N-[2-(carbamimidamidooxy)ethyl]-2-(6-chloro-2-fluo...)
Affinity DataKi:  128nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223070(N-[2-(carbamimidamidooxy)ethyl]-2-[6-chloro-2-fluo...)
Affinity DataKi:  142nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223079(N-[2-(carbamimidamidooxy)ethyl]-2-(6-chloro-3-{[2,...)
Affinity DataKi:  169nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50223080(N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-c...)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of human thrombin after 15 mins by standard chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed