Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50021152
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202222BDBM50202222(N-tert-butyl-6,7-dichloro-3-(methylsulfonyl)quinox...)
Affinity DataIC50: 32nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221632BDBM50221632(6,7-dichloro-2-(methylsulfonyl)-3-(trifluoromethyl...)
Affinity DataIC50: 91nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221625BDBM50221625(6,7-dichloro-N-isopropyl-3-(methylsulfonyl)quinoxa...)
Affinity DataIC50: 107nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221629BDBM50221629(6,7-dichloro-N-ethyl-3-(methylsulfonyl)quinoxalin-...)
Affinity DataIC50: 109nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202222BDBM50202222(N-tert-butyl-6,7-dichloro-3-(methylsulfonyl)quinox...)
Affinity DataEC50:  155nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221635BDBM50221635(N-sec-butyl-6,7-dichloro-3-(methylsulfonyl)quinoxa...)
Affinity DataEC50:  175nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221625BDBM50221625(6,7-dichloro-N-isopropyl-3-(methylsulfonyl)quinoxa...)
Affinity DataEC50:  214nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221646BDBM50221646(6,7-dichloro-2-isopropyl-3-(methylsulfonyl)quinoxa...)
Affinity DataIC50: 253nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221643BDBM50221643(6,7-dichloro-2-(methylsulfonyl)-3-propylquinoxalin...)
Affinity DataIC50: 404nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221627BDBM50221627(6,7-dichloro-3-(methylsulfonyl)-N-(1,2,3,4-tetrahy...)
Affinity DataEC50:  433nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221623BDBM50221623(2-(4-(methylsulfonyl)benzylsulfonyl)-6,7-dichloro-...)
Affinity DataIC50: 459nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221628BDBM50221628(6,7-dichloro-N-isopropyl-N-methyl-3-(methylsulfony...)
Affinity DataIC50: 460nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221631BDBM50221631(6,7-dichloro-N,N-dimethyl-3-(methylsulfonyl)quinox...)
Affinity DataIC50: 530nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221633BDBM50221633(2-(2-(1,3-dioxolan-2-yl)ethylsulfonyl)-6,7-dichlor...)
Affinity DataIC50: 551nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221651BDBM50221651(6,7-dichloro-2-(isopropylthio)-3-(methylsulfonyl)q...)
Affinity DataEC50:  661nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221629BDBM50221629(6,7-dichloro-N-ethyl-3-(methylsulfonyl)quinoxalin-...)
Affinity DataEC50:  725nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221644BDBM50221644(6,7-dichloro-2-isopropyl-3-(5-methyl-1,3,4-thiadia...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221630BDBM50221630(6,7-dichloro-2-isopropyl-3-(methylsulfinyl)quinoxa...)
Affinity DataIC50: 1.10E+3nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221643BDBM50221643(6,7-dichloro-2-(methylsulfonyl)-3-propylquinoxalin...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221623BDBM50221623(2-(4-(methylsulfonyl)benzylsulfonyl)-6,7-dichloro-...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221624BDBM50221624((6,7-dichloro-3-methanesulfonyl-quinoxalin-2-yl)-(...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221650BDBM50221650(6,7-dichloro-N-isopropyl-3-(methylsulfonyl)-8-nitr...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221628BDBM50221628(6,7-dichloro-N-isopropyl-N-methyl-3-(methylsulfony...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221631BDBM50221631(6,7-dichloro-N,N-dimethyl-3-(methylsulfonyl)quinox...)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221637BDBM50221637(N-tert-butyl-8-chloro-3-(methylsulfonyl)-6-(triflu...)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221648BDBM50221648(6,7-dichloro-2-(methylsulfonyl)-3-(pyrrolidin-1-yl...)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221638BDBM50221638(6,7-dichloro-N-methoxy-N-methyl-3-(methylsulfonyl)...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221632BDBM50221632(6,7-dichloro-2-(methylsulfonyl)-3-(trifluoromethyl...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221633BDBM50221633(2-(2-(1,3-dioxolan-2-yl)ethylsulfonyl)-6,7-dichlor...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221622BDBM50221622(ethyl 6,7-dichloro-3-(methylsulfonyl)quinoxaline-2...)
Affinity DataIC50: 3.10E+3nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221640BDBM50221640(2-(4-(cyclopropylmethylsulfonyl)benzylsulfonyl)-6,...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221636BDBM50221636(N-sec-butyl-7-chloro-3-(methylsulfonyl)-6-nitroqui...)
Affinity DataEC50:  4.30E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221645BDBM50221645(methyl 3-(4-((6,7-dichloro-3-isopropylquinoxalin-2...)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221646BDBM50221646(6,7-dichloro-2-isopropyl-3-(methylsulfonyl)quinoxa...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221647BDBM50221647(7-chloro-N-isopropyl-3-(methylsulfonyl)-6-nitro-5-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221634BDBM50221634(6,7-dichloro-2-isopropyl-3-(5-methyl-1,3,4-thiadia...)
Affinity DataEC50:  5.10E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221642BDBM50221642(6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine ...)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221621BDBM50221621(N-(2-(6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-...)
Affinity DataEC50:  7.10E+3nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221639BDBM50221639(1-(6,7-dichloro-3-isopropylquinoxalin-2-yl)-2-meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221622BDBM50221622(ethyl 6,7-dichloro-3-(methylsulfonyl)quinoxaline-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221626BDBM50221626(6,7-dichloro-N,N-diethyl-3-isopropylquinoxaline-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Effect on augmentation of [125]GLP1 binding to human GLP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221641BDBM50221641(1-(6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-yl)...)
Affinity DataEC50:  1.40E+4nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221649BDBM50221649(N'-(6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-yl...)
Affinity DataEC50:  1.40E+4nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221630BDBM50221630(6,7-dichloro-2-isopropyl-3-(methylsulfinyl)quinoxa...)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonist activity at human GLP1 assessed as stimulation of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed