Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021141
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50221438((1R,4R,9aS)-1-ethyl-4-hexyl-octahydro-1H-quinolizi...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of alpha4beta2 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50221439((1R,4R,9aS)-1-ethyl-4-(pent-4-enyl)-octahydro-1H-q...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of alpha4beta2 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50221438((1R,4R,9aS)-1-ethyl-4-hexyl-octahydro-1H-quinolizi...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of alpha-7 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50221437((1R,4R,9aS)-1-ethyl-4-(pent-4-ynyl)-octahydro-1H-q...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of alpha4beta2 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50221439((1R,4R,9aS)-1-ethyl-4-(pent-4-enyl)-octahydro-1H-q...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of alpha-7 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50221437((1R,4R,9aS)-1-ethyl-4-(pent-4-ynyl)-octahydro-1H-q...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of alpha-7 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed