Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 2231
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18313((2R,4S,5S,7S)-5-amino-N-(2-acetamidoethyl)-4-hydro...)
Affinity DataIC50: 0.300nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18288((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 0.400nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18278((2R,4S,5S,7S)-5-amino-7-{[3-(benzyloxy)-4-methoxyp...)
Affinity DataIC50: 0.600nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18289((2R,4S,5S,7S)-5-amino-4-hydroxy-N-(4-hydroxybutyl)...)
Affinity DataIC50: 0.800nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18308((2R,4S,5S,7S)-5-amino-N-(3-carbamoylpropyl)-4-hydr...)
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18306((2R,4S,5S,7S)-5-amino-N-(3-cyanopropyl)-4-hydroxy-...)
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18304(methyl 4-[(2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-me...)
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18287((2R,4S,5S,7S)-5-amino-4-hydroxy-N-(3-hydroxypropyl...)
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18294((2R,4S,5S,7S)-5-amino-N-{2-[(2R,6S)-2,6-dimethylmo...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18293((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18295((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18297((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18298((2R,4S,5S,7S)-5-amino-N-[2-(1,1-dioxo-1,4-thiomorp...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18310((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18311((2R,4S,5S,7S)-5-amino-N-(4-carbamoylbutyl)-4-hydro...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18312((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18316((2R,4S,5S,7S)-5-amino-N-[2-(dimethylsulfamoyl)ethy...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18320((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18284((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18319((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 3nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18302(4-[(2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3...)
Affinity DataIC50: 3nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18309((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 3nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18282((2R,4S,5S,7S)-5-amino-N-butyl-7-{[3-(3-ethoxypropo...)
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18270(methyl 2-{5-[(2S,4S,5S,7R)-4-amino-7-(butylcarbamo...)
Affinity DataIC50: 4nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18286((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)
Affinity DataIC50: 4nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18303(ethyl 3-[(2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-met...)
Affinity DataIC50: 4nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18280((2R,4S,5S,7S)-5-amino-N-butyl-7-{[3-(2-ethoxyethox...)
Affinity DataIC50: 4nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18314((2R,4S,5S,7S)-5-amino-N-[2-(ethanesulfonyl)ethyl]-...)
Affinity DataIC50: 4nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18318((2R,4S,5S,7S)-5-amino-4-hydroxy-N-[3-(1H-imidazol-...)
Affinity DataIC50: 4nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18300((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 5nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18277((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)
Affinity DataIC50: 5nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18315((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 6nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18269(methyl 2-{5-[(2S,4S,5S,7R)-4-amino-7-(butylcarbamo...)
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18283((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[3-(3-h...)
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18305(4-[(2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3...)
Affinity DataIC50: 6nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18307((2R,4S,5S,7S)-5-amino-N-(2-carbamoylethyl)-4-hydro...)
Affinity DataIC50: 7nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18317((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 8nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18299((2R,4S,5S,7S)-5-amino-4-hydroxy-N-[2-(4-hydroxypip...)
Affinity DataIC50: 10nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18279((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)
Affinity DataIC50: 11nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18296((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 11nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18301(3-[(2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3...)
Affinity DataIC50: 12nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18274((2R,4S,5S,7S)-5-amino-N-butyl-7-{[4-tert-butyl-3-(...)
Affinity DataIC50: 13nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18291((2R,4S,5S,7S)-5-amino-N-(3-aminopropyl)-4-hydroxy-...)
Affinity DataIC50: 16nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18290((2R,4S,5S,7S)-5-amino-N-[2-(dimethylamino)ethyl]-4...)
Affinity DataIC50: 18nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18285((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-({4-meth...)
Affinity DataIC50: 19nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18271((2R,4S,5S,7S)-5-amino-N-butyl-7-{[4-tert-butyl-3-(...)
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18292((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 22nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18276((2R,4S,5S,7S)-5-amino-N-butyl-7-{[4-tert-butyl-3-(...)
Affinity DataIC50: 26nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18273((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-({4-meth...)
Affinity DataIC50: 42nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
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