Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50021093
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM27709(CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220858((S)-8-chloro-2-(3-(4-phenylpiperidin-1-yl)cyclopen...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220868(2-(3-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220878(2-(3-(4-(4-chlorophenyl)piperazin-1-yl)cyclopent-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220859((S)-8-chloro-2-(3-(4-phenyl-5,6-dihydropyridin-1(2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220877(2-(3-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220862(2-(3-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)cyclope...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM27705(2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)prop...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220864(2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220882(2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220883(8-chloro-2-(3-(4-(4-fluorophenyl)piperazin-1-yl)cy...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220875(2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220861(2-(3-(4-(4-chlorophenyl)piperazin-1-yl)cyclopent-1...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM27706(CHEMBL251029 | 8-chloro-2-[3-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220880(2-(3-(4-(4-fluorophenyl)piperidin-1-yl)cyclopent-1...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220876((S)-8-chloro-2-(3-(4-(4-fluorophenyl)piperidin-1-y...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220874(8-chloro-2-(3-(4-(4-fluorophenyl)-5,6-dihydropyrid...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220863(2-(3-(4-(4-chlorophenyl)piperidin-1-yl)cyclopent-1...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220856(2-[3-(4-Phenyl-piperidin-1-yl)-propyl]-3H-quinazol...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220879(8-chloro-2-(3-(4-(4-fluorophenyl)piperidin-1-yl)pr...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220869(8-chloro-2-(3-(4-phenylpiperidin-1-yl)propyl)quina...)
Affinity DataIC50: 103nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220871(2-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)piperid...)
Affinity DataIC50: 131nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220865(2-(3-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)cyclohe...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220873((R)-8-chloro-2-(3-(4-(4-fluorophenyl)piperidin-1-y...)
Affinity DataIC50: 257nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220866((R)-8-chloro-2-(3-(4-phenyl-5,6-dihydropyridin-1(2...)
Affinity DataIC50: 286nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220872(2-(3-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)pyrroli...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220881(2-(3-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)azetidi...)
Affinity DataIC50: 504nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220867(2-(3-(4-phenylpiperidin-1-yl)cyclopentyl)quinazoli...)
Affinity DataIC50: 555nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220867(2-(3-(4-phenylpiperidin-1-yl)cyclopentyl)quinazoli...)
Affinity DataIC50: 555nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220870(2-((1s,4s)-4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220860(2-(3-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)cyclohe...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50220857(2-((1r,4r)-4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed