Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50042265
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130785(CHEMBL609978 | CHEMBL542453 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128063(CHEMBL67133 | CHEMBL112210 | Allyl-{6-[3-(4-bromo-...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128054(N-allyl-6-(1-(4-bromophenyl)isoquinolin-6-yloxy)-N...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130788(CHEMBL611484 | CHEMBL116705 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128055(CHEMBL66638 | CHEMBL115085 | Allyl-{6-[4-(4-bromo-...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130783(CHEMBL115020 | CHEMBL611485 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128050(CHEMBL114259 | CHEMBL416694 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130786(CHEMBL611486 | CHEMBL115923 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130774(CHEMBL611757 | CHEMBL115375 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128065({4-[6-(Allyl-methyl-amino)-hexyloxy]-2-fluoro-phen...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130775(CHEMBL554209 | CHEMBL611758 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50423108(CHEMBL612024)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130784(Allyl-{6-[1-(4-bromo-phenyl)-3,4-dihydro-isoquinol...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130787(CHEMBL114266 | CHEMBL612025 | {6-[6-(Allyl-methyl-...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130776(N-allyl-6-(4-(4-bromophenyl)-2H-chromen-7-yloxy)-N...)
Affinity DataIC50: 11nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130781(CHEMBL612026 | CHEMBL419402 | Allyl-{6-[4-(4-bromo...)
Affinity DataIC50: 12nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128064(N-allyl-4-(3-(4-bromophenyl)benzo[b]thiophen-6-ylo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130777(CHEMBL114910 | CHEMBL611487 | (4-Bromo-phenyl)-(4-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50423111(CHEMBL611754)
Affinity DataIC50: 19nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 19nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130779(CHEMBL553281 | CHEMBL611755 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128061(N-(((1S,2S)-2-((4-(4-bromobenzoyl)phenoxy)methyl)c...)
Affinity DataIC50: 22nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128067((E)-N-allyl-4-(3-(4-bromophenyl)-5-fluoro-1-methyl...)
Affinity DataIC50: 29nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128046(N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6-ylo...)
Affinity DataIC50: 29nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130771(CHEMBL114747 | CHEMBL611756 | (4-Bromo-phenyl)-{4-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50130778(CHEMBL544345 | CHEMBL612027 | (4-Bromo-phenyl)-{4-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128051(N-allyl-6-(3-(4-bromophenyl)-1H-indazol-6-yloxy)-N...)
Affinity DataIC50: 39nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128057(N-(6-(1-(4-fluorobenzoyl)piperidin-4-yloxy)hexyl)-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128059(N-allyl-6-(1-(4-fluorobenzoyl)piperidin-4-yloxy)-N...)
Affinity DataIC50: 71nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128048(N-(6-(4-(4-bromobenzoyl)-3-fluorophenoxy)hexyl)-N-...)
Affinity DataIC50: 98nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128072({4-[((1S,2S)-2-{[ALLYL(CYCLOPROPYL)AMINO]METHYL}CY...)
Affinity DataIC50: 224nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50412870(CHEMBL612028)
Affinity DataIC50: 240nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128069(N-(((1S,2S)-2-((4-(4-bromobenzoyl)-3-fluorophenoxy...)
Affinity DataIC50: 437nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128056(CHEMBL481811 | CHEMBL65553 | ALLYL-{4-[3-(4-BROMO-...)
Affinity DataIC50: 501nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128045(Allyl-{6-[3-(4-bromo-phenyl)-benzofuran-6-yloxy]-h...)
Affinity DataIC50: 617nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128047(N-allyl-4-(4-(6-bromobenzo[d]isothiazol-3-yl)pheno...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50128052(Allyl-{6-[4-(6-bromo-benzo[d]isothiazol-3-yl)-phen...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed