Compile Data Set for Download or QSAR
Report error Found 109 Enz. Inhib. hit(s) with all data for entry = 50020891
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218730(3-(3-methoxy-4-nitrophenyl)-8-(2-oxopyrrolidin-1-y...)
Affinity DataEC50:  4.95E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218701(8-(1,1-dioxo-1l6-isothiazolidin-2-yl)-3-(3-methoxy...)
Affinity DataEC50:  9.00E+3nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218719(8-methoxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataEC50: >5.93E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218712(3-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cell cycle arrest in HeLa cells assessed as accumulation at G2/M phase by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218720(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cell cycle arrest in HeLa cells assessed as accumulation at G2/M phase by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218703(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cell cycle arrest in HeLa cells assessed as accumulation at G2/M phase by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218733(3-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50:  5.19E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218709(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >5.93E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218700(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >5.93E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218704(3-(4-amino-3-methoxy-phenyl)-7-morpholin-4-yl-5,10...)
Affinity DataEC50:  4.61E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218723(7-amino-3-(4-amino-3-methoxy-phenyl)-5,10-dihydro-...)
Affinity DataEC50:  4.99E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218701(8-(1,1-dioxo-1l6-isothiazolidin-2-yl)-3-(3-methoxy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218704(3-(4-amino-3-methoxy-phenyl)-7-morpholin-4-yl-5,10...)
Affinity DataEC50:  2.10E+3nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218711(8-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataEC50: >5.93E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218700(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218703(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >5.93E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218715(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50:  2.63E+3nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218720(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50:  3.25E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218723(7-amino-3-(4-amino-3-methoxy-phenyl)-5,10-dihydro-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218712(3-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >5.93E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218706(methyl [3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-d...)
Affinity DataEC50:  890nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218733(3-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218719(8-methoxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218709(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218730(3-(3-methoxy-4-nitrophenyl)-8-(2-oxopyrrolidin-1-y...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218733(3-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218701(8-(1,1-dioxo-1l6-isothiazolidin-2-yl)-3-(3-methoxy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218706(methyl [3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-d...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218704(3-(4-amino-3-methoxy-phenyl)-7-morpholin-4-yl-5,10...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218730(3-(3-methoxy-4-nitrophenyl)-8-(2-oxopyrrolidin-1-y...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218720(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218715(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218723(7-amino-3-(4-amino-3-methoxy-phenyl)-5,10-dihydro-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218709(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218700(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218703(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218722(3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b,e][1,4]di...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218712(3-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218711(8-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218719(8-methoxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218710(6-methoxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218741(8-amino-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b,e...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218732(2-methoxy-4-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218717(3-(4-acetyl-3-methoxy-phenyl)-5,10-dihydro-dibenzo...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218724(methyl 2-methoxy-4-(11-oxo-10,11-dihydro-5H-dibenz...)
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218713(9-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218738(3-(4-hydroxy-3-methoxyphenyl)-5H-dibenzo[b,e][1,4]...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218740(2-methoxy-4-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218721(3-(4-chloro-3-methoxy-phenyl)-5,10-dihydro-dibenzo...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218728(3-(3-methoxy-4-nitrophenyl)-6-(pyridin-4-ylmethoxy...)
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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