Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50032221
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326011(Okicenone | CHEMBL1240971)
Affinity DataKd:  90nMAssay Description:Binding affinity to HuR after 24 hrs by microdialysis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  14nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(Dehydromutactin | CHEMBL1242196)
Affinity DataKd:  0.0100nMAssay Description:Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  0.100nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(Dehydromutactin | CHEMBL1242196)
Affinity DataKd:  0.100nMAssay Description:Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(Dehydromutactin | CHEMBL1242196)
Affinity DataKd:  9nMAssay Description:Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectrosc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(Dehydromutactin | CHEMBL1242196)
Affinity DataKd:  6nMAssay Description:Binding affinity to recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  230nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  420nMAssay Description:Binding affinity recombinant HuR RRM1/RRM2 domain by confocal fluctuation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  0.100nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(Dehydromutactin | CHEMBL1242196)
Affinity DataKd:  9nMAssay Description:Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectrosc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326011(Okicenone | CHEMBL1240971)
Affinity DataKd:  85nMAssay Description:Binding affinity to recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetMyosin light chain kinase, smooth muscle(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MYLKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed