Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50037952
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataEC50:  0.470nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  0.350nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataEC50:  6.10nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataIC50: 0.770nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 22nMAssay Description:Inhibition of rat CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218121(naphthalen-1-yl-(4-pentylaminonaphthalen-1-yl)meth...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218123(naphthalen-1-yl-(4-butoxynaphthalen-1-yl)methanone...)
Affinity DataIC50: 48nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218123(naphthalen-1-yl-(4-butoxynaphthalen-1-yl)methanone...)
Affinity DataIC50: 85nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218120(naphthalen-1-yl-(4-propoxynaphthalen-1-yl)methanon...)
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218121(naphthalen-1-yl-(4-pentylaminonaphthalen-1-yl)meth...)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218119((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218120(naphthalen-1-yl-(4-propoxynaphthalen-1-yl)methanon...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218119((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Affinity DataIC50: 660nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218122(naphthalen-1-yl-(4-phenethyloxynaphthalen-1-yl)met...)
Affinity DataIC50: 930nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218118([4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]naphtha...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218122(naphthalen-1-yl-(4-phenethyloxynaphthalen-1-yl)met...)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218118([4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]naphtha...)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 8.08E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2E1 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed