Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50038411
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to Helicobacter pylori MurI by protein fluorescence binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM50215445(5-(2-((6-chloroquinolin-4-yl)methyl)-7-(cyclopropy...)
Affinity DataKd:  25nMAssay Description:Binding affinity to Helicobacter pylori MurI by protein fluorescence binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to Helicobacter pylori MurI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM50215445(5-(2-((6-chloroquinolin-4-yl)methyl)-7-(cyclopropy...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Helicobacter pylori glutamate racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Helicobacter pylori glutamate racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Streptococcus pneumoniae D39)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MurI in Streptococcus pneumoniaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlutamate racemase(Streptococcus pneumoniae D39)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM50215445(5-(2-((6-chloroquinolin-4-yl)methyl)-7-(cyclopropy...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MurI in Streptococcus pneumoniaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of Helicobacter pylori glutamate racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed