Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50038028
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50368628(ABT-569 | Abbott-70569 | Abbott-70569.1 | Gabitril...)
Affinity DataIC50: 80nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50371220(CHEMBL538839)
Affinity DataIC50: 920nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50371217(CHEMBL558578)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213498((R)-1-(3-(benzhydrylthio)propyl)piperidine-3-carbo...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213501((R)-1-(3-(dip-tolylmethylthio)propyl)piperidine-3-...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213497((3R)-1-(3-((2,3-dimethylphenyl)(o-tolyl)methylthio...)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50371219(CHEMBL536762)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213503((R)-1-(3-(bis(4-methoxyphenyl)methylthio)propyl)pi...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213502((R)-1-(2-(dip-tolylmethylthio)ethyl)piperidine-3-c...)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50020883(CHEMBL77575 | (R)-Piperidine-3-carboxylic acid | N...)
Affinity DataIC50: 4.56E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50371218(CHEMBL536534)
Affinity DataIC50: 5.89E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213496((R)-1-(2-(benzhydrylthio)ethyl)piperidine-3-carbox...)
Affinity DataIC50: 1.60E+6nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213506((3R)-1-(2-((2,3-dimethylphenyl)(o-tolyl)methylthio...)
Affinity DataIC50: 2.13E+6nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50213507((R)-1-(2-(bis(4-methoxyphenyl)methylthio)ethyl)pip...)
Affinity DataIC50: 4.80E+6nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed