Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50020413
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM21279(N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-5-(4-iod...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213486(N-(4-phenylbutan-2-yl)-5,6-dip-tolylpyrazine-2-car...)
Affinity DataKi:  5nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213468((S)-5,6-bis(4-chlorophenyl)-N-(1-hydroxy-4-methylp...)
Affinity DataKi:  14nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213467(N-(3-phenylpropyl)-5,6-dip-tolylpyrazine-2-carboxa...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213462(N-(3-(methyl(phenyl)amino)propyl)-5,6-dip-tolylpyr...)
Affinity DataKi:  25nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213468((S)-5,6-bis(4-chlorophenyl)-N-(1-hydroxy-4-methylp...)
Affinity DataKi:  30nMAssay Description:Binding affinity to rat CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213478(N-(1-hydroxy-2,3-dihydro-1H-inden-2-yl)-5,6-dip-to...)
Affinity DataKi:  33nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213465((S)-N-(1-hydroxy-4-methylpentan-2-yl)-5,6-dip-toly...)
Affinity DataKi:  35nMAssay Description:Binding affinity to rat CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213477(N-(1-(2,6-dimethylphenoxy)propan-2-yl)-5,6-dip-tol...)
Affinity DataKi:  39nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213465((S)-N-(1-hydroxy-4-methylpentan-2-yl)-5,6-dip-toly...)
Affinity DataKi:  45nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213479(N-((1R,2R)-2-(hydroxymethyl)cyclohexyl)-5,6-dip-to...)
Affinity DataKi:  50nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM35871(N-(piperidin-1-yl)-5,6-dip-tolylpyrazine-2-carboxa...)
Affinity DataKi:  53nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213476(N-(cyclohexylmethyl)-5,6-dip-tolylpyrazine-2-carbo...)
Affinity DataKi:  59nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213467(N-(3-phenylpropyl)-5,6-dip-tolylpyrazine-2-carboxa...)
Affinity DataKi:  80nMAssay Description:Binding affinity to rat CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213471((S)-N-(1-amino-4-methyl-1-oxopentan-2-yl)-5,6-dip-...)
Affinity DataKi:  105nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213472(N-benzyl-N-methyl-5,6-dip-tolylpyrazine-2-carboxam...)
Affinity DataKi:  110nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213470(N-(1-hydroxypentan-2-yl)-5,6-dip-tolylpyrazine-2-c...)
Affinity DataKi:  158nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213480(N-((1R,2S)-2-(hydroxymethyl)cyclohexyl)-5,6-dip-to...)
Affinity DataKi:  167nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213475(N-isopentyl-5,6-dip-tolylpyrazine-2-carboxamide | ...)
Affinity DataKi:  178nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213466(N-(cyclopropylmethyl)-5,6-dip-tolylpyrazine-2-carb...)
Affinity DataKi:  178nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213464(N-(1-(benzyloxy)butan-2-yl)-5,6-dip-tolylpyrazine-...)
Affinity DataKi:  203nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213484((S)-N-(1-hydroxy-3-methylbutan-2-yl)-5,6-dip-tolyl...)
Affinity DataKi:  237nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213463((R)-N-(2-amino-2-oxo-1-phenylethyl)-5,6-dip-tolylp...)
Affinity DataKi:  238nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213473(N-((1R,2S)-2-hydroxycyclohexyl)-5,6-dip-tolylpyraz...)
Affinity DataKi:  300nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213483((R)-N-(1-hydroxy-3-methylbutan-2-yl)-5,6-dip-tolyl...)
Affinity DataKi:  316nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213485((R)-N-(1-hydroxy-4-methylpentan-2-yl)-5,6-dip-toly...)
Affinity DataKi:  460nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM35881(N-phenyl-5,6-dip-tolylpyrazine-2-carboxamide | 5,6...)
Affinity DataKi:  509nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213482(N-(2-phenoxyethyl)-5,6-dip-tolylpyrazine-2-carboxa...)
Affinity DataKi:  631nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213487(N-isopropyl-5,6-dip-tolylpyrazine-2-carboxamide | ...)
Affinity DataKi:  656nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213481(N-ethyl-5,6-dip-tolylpyrazine-2-carboxamide | CHEM...)
Affinity DataKi:  2.38E+3nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213469(N-methyl-5,6-dip-tolylpyrazine-2-carboxamide | CHE...)
Affinity DataKi:  3.85E+3nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50213474(N-(2-hydroxyethyl)-5,6-dip-tolylpyrazine-2-carboxa...)
Affinity DataKi:  8.43E+3nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed