Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50004056
TargetRNA-directed RNA polymerase(Hepacivirus C)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50333128(((2S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-...)
Affinity DataIC50: 770nMAssay Description:Inhibition of HCV NS5B polymerase S282T mutant assessed as blocking of full length RNA product formation by single-nucleotide incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM86487(NSC_0 | CAS_0 | ATP,3'-deoxy)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of HCV NS5B polymerase S282T mutant assessed as blocking of full length RNA product formation by single-nucleotide incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50478972(2''C-Me-CTP | CHEMBL223585)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of HCV NS5B polymerase S282T mutant assessed as blocking of full length RNA product formation by single-nucleotide incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50478971(2''C-Me-ATP | CHEMBL374931)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HCV NS5B polymerase S282T mutant assessed as blocking of full length RNA product formation by single-nucleotide incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed