Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 2325
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19443(2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy...)
Affinity DataIC50: 7.80nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19443(2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy...)
Affinity DataIC50: 9.60nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19446(2-phenyl-3-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1...)
Affinity DataIC50: 10.9nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19446(2-phenyl-3-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1...)
Affinity DataIC50: 16.3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19444(2-(4-fluorophenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]...)
Affinity DataIC50: 17.2nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19448(2-(4-aminophenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]p...)
Affinity DataIC50: 19.3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 20.6nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy...)
Affinity DataIC50: 21.5nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19445(2-(4-bromophenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]p...)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19447(CHEMBL389907 | 2-(4-methanesulfonylphenyl)-3-{4-[2...)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19444(2-(4-fluorophenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]...)
Affinity DataIC50: 27.9nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19450(2-{4-[(2-chloroethyl)amino]phenyl}-3-{4-[2-(piperi...)
Affinity DataIC50: 35.6nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19448(2-(4-aminophenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]p...)
Affinity DataIC50: 48.6nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy...)
Affinity DataIC50: 66.3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19445(2-(4-bromophenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]p...)
Affinity DataIC50: 66.7nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 557nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19449(2-chloro-N-[4-(6-hydroxy-3-{4-[2-(piperidin-1-yl)e...)
Affinity DataIC50: 666nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19450(2-{4-[(2-chloroethyl)amino]phenyl}-3-{4-[2-(piperi...)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19447(CHEMBL389907 | 2-(4-methanesulfonylphenyl)-3-{4-[2...)
Affinity DataIC50: 1.80E+3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19449(2-chloro-N-[4-(6-hydroxy-3-{4-[2-(piperidin-1-yl)e...)
Affinity DataIC50: 2.36E+3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed