Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50020232
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211482(1-(2,4-difluoro-phenyl)-3-(3,5a,10-trimethyl-2-oxo...)
Affinity DataIC50: 600nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211496(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 800nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211491(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211478(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 800nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211495(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211488(N-(furan-2-ylmethyl)-2-(7-methoxy-5,8-dimethyl-1,2...)
Affinity DataIC50: 900nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211483(3,4,5-trimethoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a...)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211491(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211496(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211489(2-(7-(2-(dimethylamino)ethoxy)-5,8-dimethyl-1,2,3,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211484(1-(3-methylsulfanyl-phenyl)-3-(3,5a,10-trimethyl-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211481(benzo[1,3]dioxole-5-carboxylic acid (3,5a,10-trime...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211479(1-benzyl-3-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211490(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211485(2-(2-methoxy-phenyl)-N-(3,5a,10-trimethyl-2-oxo-2,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211487(N-tert-butyl-2-(7-methoxy-5,8-dimethyl-1,2,3,4-tet...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211484(1-(3-methylsulfanyl-phenyl)-3-(3,5a,10-trimethyl-2...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211478(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211480(4-methoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211495(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211482(1-(2,4-difluoro-phenyl)-3-(3,5a,10-trimethyl-2-oxo...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211492(cyclopentanecarboxylic acid (3,5a,10-trimethyl-2-o...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211494(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211490(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211492(cyclopentanecarboxylic acid (3,5a,10-trimethyl-2-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211486(4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211494(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211489(2-(7-(2-(dimethylamino)ethoxy)-5,8-dimethyl-1,2,3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211480(4-methoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211479(1-benzyl-3-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211493(N-cyclopentyl-2-[7-(2-methoxy-ethoxy)-5,8-dimethyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211488(N-(furan-2-ylmethyl)-2-(7-methoxy-5,8-dimethyl-1,2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211493(N-cyclopentyl-2-[7-(2-methoxy-ethoxy)-5,8-dimethyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211485(2-(2-methoxy-phenyl)-N-(3,5a,10-trimethyl-2-oxo-2,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211481(benzo[1,3]dioxole-5-carboxylic acid (3,5a,10-trime...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211487(N-tert-butyl-2-(7-methoxy-5,8-dimethyl-1,2,3,4-tet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211486(4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211483(3,4,5-trimethoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed