Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50025181
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM26736(N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242643(N,N-dimethyl-5-((7-phenylheptanamido)methyl)-2H-te...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242636(N,N-Dimethyl-5-(3-phenylpropyl)-1H-tetrazole-1-car...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242645(N,N-dimethyl-5-((7-phenyloctanamido)methyl)-2H-tet...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242638(N,N-dimethyl-5-(3-phenylpropyl)-2Htetrazole-2-carb...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242637(N,N-dimethyl-5-phenethyl-2H-tetrazole-2-carboxamid...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242675(N,N-Dimethyl-5-((7-phenylheptanamido)methyl)-1H-te...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242635(N,N-Dimethyl-5-phenethyl-1H-tetrazole-1-carboxamid...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242642(5-(Biphenyl-4-ylcarboxamidomethyl)-N,N-dimethyl-2H...)
Affinity DataIC50: 6nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242640(N,N-Dimethyl-5-((7-phenyloctanamido)methyl)-1Htetr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242639(5-((4-Azido-3-iodobenzamido)methyl)-N,N-dimethyl-1...)
Affinity DataIC50: 23nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242641(5-(biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-2H...)
Affinity DataIC50: 23nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242674(5-((4-azido-3-iodobenzamido)methyl)-N,N-dimethyl-2...)
Affinity DataIC50: 25nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242644(5-(Biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-1H...)
Affinity DataIC50: 32nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242634(5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazol...)
Affinity DataIC50: 33nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242639(5-((4-Azido-3-iodobenzamido)methyl)-N,N-dimethyl-1...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242675(N,N-Dimethyl-5-((7-phenylheptanamido)methyl)-1H-te...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242644(5-(Biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-1H...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242638(N,N-dimethyl-5-(3-phenylpropyl)-2Htetrazole-2-carb...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242634(5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazol...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242640(N,N-Dimethyl-5-((7-phenyloctanamido)methyl)-1Htetr...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242637(N,N-dimethyl-5-phenethyl-2H-tetrazole-2-carboxamid...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242674(5-((4-azido-3-iodobenzamido)methyl)-N,N-dimethyl-2...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242645(N,N-dimethyl-5-((7-phenyloctanamido)methyl)-2H-tet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242635(N,N-Dimethyl-5-phenethyl-1H-tetrazole-1-carboxamid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242636(N,N-Dimethyl-5-(3-phenylpropyl)-1H-tetrazole-1-car...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242641(5-(biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242642(5-(Biphenyl-4-ylcarboxamidomethyl)-N,N-dimethyl-2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242643(N,N-dimethyl-5-((7-phenylheptanamido)methyl)-2H-te...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM26736(N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed