Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50037911
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211148((R)-N-(1-(4-oxo-3-(4-(prop-1-ynyl)phenyl)-3,4-dihy...)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human CXCR3 assessed as inhibition of ITAC-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211138((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211130((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211137((R)-N-(1-(3-(4-nitrophenyl)-4-oxo-3,4-dihydroquina...)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50: 8nMAssay Description:Inhibition of IP10-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I] ITAC from the CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211128(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-1-[3-(4-...)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211121((R)-N-(1-(3-(4-cyanophenyl)-4-oxo-3,4-dihydroquina...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211123(CHEMBL553862 | CHEMBL230560 | (R)-N-(1-(3-(4-fluor...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211123(CHEMBL553862 | CHEMBL230560 | (R)-N-(1-(3-(4-fluor...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211143((R)-N-(1-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroqui...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50: 15nMAssay Description:Inhibition of ITAC-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211122((R)-N-(1-(3-(4-chlorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211115((R)-N-(1-(4-oxo-3-p-tolyl-3,4-dihydroquinazolin-2-...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50: 36nMAssay Description:Inhibition of MIG-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211119((R)-N-(2-ethoxyethyl)-N-(1-(3-(4-fluorophenyl)-4-o...)
Affinity DataIC50: 40nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211118((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 73nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211156(2-biphenyl-4-yl-N-(2-dimethylamino-ethyl)-N-{(R)-1...)
Affinity DataIC50: 75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211132(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-1-[3-(4-...)
Affinity DataIC50: 75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211117((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 88nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211129((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211152((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyri...)
Affinity DataIC50: 144nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211140((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 146nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211151((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 154nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211150((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 156nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211145((R)-N-(2-(1H-imidazol-2-yl)-2-oxoethyl)-N-(1-(3-(4...)
Affinity DataIC50: 230nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211144((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 240nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50167778(N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluorophenyl...)
Affinity DataIC50: 250nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211142((R)-N-(1-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-y...)
Affinity DataIC50: 299nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211157((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 300nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211155((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 375nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211147((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropter...)
Affinity DataIC50: 480nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50167778(N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluorophenyl...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human CXCR3 assessed as inhibition of MIG-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211120((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 587nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211153((R)-N-(2-(1H-imidazol-4-yl)-2-oxoethyl)-N-(1-(3-(4...)
Affinity DataIC50: 650nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211134((R)-2-(1-((2-(dimethylamino)ethyl)(nonyl)amino)eth...)
Affinity DataIC50: 710nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211125((R)-2-(1-((2-(dimethylamino)ethyl)(octyl)amino)eth...)
Affinity DataIC50: 790nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211154((R)-4-(4-oxo-2-(1-(N-(pyridin-3-ylmethyl)-2-(4-(tr...)
Affinity DataIC50: 1.37E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211149((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211136((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyri...)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211135(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-[3-(4-ethoxy-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211146(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-[3-(4-et...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211127((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211131(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{1-[3-(4-etho...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211126((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211133((R)-N-(1-(3-(4-(methylsulfonyl)phenyl)-4-oxo-3,4-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211158((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50211159((S)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
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