Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50020085
TargetPlasma kallikrein(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataKi:  2nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataKi:  4nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataKi:  17nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataKi:  154nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataKi:  367nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed