Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50032220
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326005(4,4'-(1H-indazol-6-ylazanediyl)bis(methylene)diben...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326005(4,4'-(1H-indazol-6-ylazanediyl)bis(methylene)diben...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human GST-fused Src-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326008(4-((7,7a-dihydrobenzo[d][1,3]dioxol-5-ylamino)meth...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326004(4-((1H-indazol-6-ylamino)methyl)benzene-1,2-diol |...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326007(4,4'-(naphthalen-2-ylazanediyl)bis(methylene)diben...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326003(4-((benzo[d][1,3]dioxol-5-ylamino)methyl)benzene-1...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326003(4-((benzo[d][1,3]dioxol-5-ylamino)methyl)benzene-1...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human GST-fused Src-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326003(4-((benzo[d][1,3]dioxol-5-ylamino)methyl)benzene-1...)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326004(4-((1H-indazol-6-ylamino)methyl)benzene-1,2-diol |...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326007(4,4'-(naphthalen-2-ylazanediyl)bis(methylene)diben...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human LNCaP cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326006(4-((naphthalen-2-ylamino)methyl)benzene-1,2-diol |...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326006(4-((naphthalen-2-ylamino)methyl)benzene-1,2-diol |...)
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human MCF7 cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human PC3 cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50326008(4-((7,7a-dihydrobenzo[d][1,3]dioxol-5-ylamino)meth...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed