Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50037845
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370912(CHEMBL1202309)
Affinity DataKi:  8nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370916(CHEMBL1202310)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50208721(CHEMBL1204123 | CHEMBL223324 | 4-(biphenyl-3-yl)-5...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50208717(4-(bromo(naphthalen-2-yl)methyl)-5-(piperidin-4-yl...)
Affinity DataKi:  42nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370917(CHEMBL1202300)
Affinity DataKi:  48nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370918(CHEMBL1202304)
Affinity DataKi:  59nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370915(CHEMBL1202302)
Affinity DataKi:  68nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370911(CHEMBL1202308)
Affinity DataKi:  71nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370913(CHEMBL1202306)
Affinity DataKi:  76nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370914(CHEMBL1202299)
Affinity DataKi:  129nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370921(CHEMBL1202303)
Affinity DataKi:  138nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50159237(4-Naphthalen-2-yl-5-piperidin-4-yl-isoxazol-3-ol |...)
Affinity DataKi:  141nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50159235(4-phenyl-5-(4-piperidyl)-3-isoxazolol | 4-Phenyl-5...)
Affinity DataKi:  159nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50159239(4-(1-Phenyl-naphthalen-2-ylmethyl)-5-piperidin-4-y...)
Affinity DataKi:  198nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370910(CHEMBL1202301)
Affinity DataKi:  204nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370919(CHEMBL1202307)
Affinity DataKi:  257nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50159229(4-Naphthalen-1-yl-5-piperidin-4-yl-isoxazol-3-ol |...)
Affinity DataKi:  334nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50095533(CHEMBL144718 | 4-(naphthalen-2-ylmethyl)-5-(piperi...)
Affinity DataKi:  370nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50370909(CHEMBL1202305)
Affinity DataKi:  427nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50032954(5-Piperidin-4-yl-isoxazol-3-ol(4-PIOL) | 5-(piperi...)
Affinity DataKi:  1.10E+4nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed