Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019890
TargetSodium/glucose cotransporter 2(Human)
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 1(Human)
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM50208612(kurarinone | (-)-kurarinone | (2S)-2-(2,4-dihydrox...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM50208612(kurarinone | (-)-kurarinone | (2S)-2-(2,4-dihydrox...)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed