Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50019674
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206591(methyl (1R,2S/1S,2R)-2-[(4-benzylpiperidin-1-yl)me...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206586(methyl (1R,2S/1S,2R)-2-[(4-benzylpiperidin-1-yl)me...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206593(methyl (1R,2S/1S,2R)-2-[(4-benzylpiperidin-1-yl)me...)
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206579(methyl (1R,2S/1S,2R)-2-[(4-benzylpiperidin-1-yl)me...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206589(methyl (1R,2S/1S,2R)-1-(4-chlorophenyl)-2-[(4-hydr...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206585(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206580(methyl (1R,2S/1S,2R)-2-[(4-benzylpiperidin-1-yl)me...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206597(methyl (1R,2S/1S,2R)-2-[(4-Hydroxy-4-phenylpiperid...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206590(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206577(CHEMBL222287 | 10-methoxyibogamine | IBOGAINE)
Affinity DataKi:  250nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206596(methyl (1R,2S/1S,2R)-1-(4-chlorophenyl)-2-[(4-pyri...)
Affinity DataKi:  350nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206582(methyl (1R,2S/1S,2R)-1-(4-methylphenyl)-2-[(4-pyri...)
Affinity DataKi:  353nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206595(methyl (1R,2S/1S,2R)-1-(4-methylphenyl)-2-[(4-pyri...)
Affinity DataKi:  497nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206598(methyl (1R,2S/1S,2R)-(4-nitrophenyl)-2-[(4-pyrimid...)
Affinity DataKi:  619nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206594(methyl (1R,2S/1S,2R)-1-(4-chlorophenyl)-2-[(4-pyri...)
Affinity DataKi:  707nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206576(methyl (1R,2S/1S,2R)-1-(4-nitrophenyl)-2-[(4-pyrid...)
Affinity DataKi:  769nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206592(methyl (1R,2S/1S,2R)-1-(4-methoxyphenyl)-2-[(4-pyr...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [3H]spiperone from rat striatum dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206587(methyl (1R,2S/1S,2R)-1-phenyl-2-[(4-pyridin-2-ylpi...)
Affinity DataKi:  1.33E+3nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.42E+3nMAssay Description:Displacement of [3H]pyrilamine from rat cortex histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206584(methyl (1R,2S/1S,2R)-1-(4-methoxyphenyl)-2-[(4-pyr...)
Affinity DataKi:  2.03E+3nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206583(methyl (1R,2S/1S,2R)-1-phenyl-2-[(4-pyrimidin-2-yl...)
Affinity DataKi:  3.09E+3nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  3.15E+3nMAssay Description:Displacement of [3H]ketanserin from rat cortex 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  4.36E+3nMAssay Description:Displacement of [3H]mesulergine from guinea pig cortex 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [3H]7OH-DPAT from rat olfactory tubercle dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from rat striatum dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5HT from rat cloned 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206588(methyl (1R,2S/1S,2R)-1-(4-aminophenyl)-2-[(4-pyrim...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]citalopram from rat cortex SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206581(methyl (1R,2S/1S,2R)-1-(4-aminophenyl)-2-[(4-pyrid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]GR-13808 from guinea pig cortex 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN-35428 from rat striatum DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LY278584 from rat cortex 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed