Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022546
TargetSerine/threonine-protein kinase PLK1(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 9.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 360nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 4.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 11(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
GlaxoSmithKline R & D

Curated by ChEMBL
LigandPNGBDBM25120(BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed