Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50019209
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202759(N-(4-(4-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin...)
Affinity DataIC50: 31nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(N-(4-(4-amino-7-(3-((1r,4r)-4-aminocyclohexylamino...)
Affinity DataIC50: 110nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202757(N-(4-(4-amino-7-(3-oxo-3-(piperidin-4-ylamino)prop...)
Affinity DataIC50: 130nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202733(4-amino-N-(2-(dimethylamino)ethyl)-3-(3-methoxy-4-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(N-(4-(4-amino-7-(3-(piperidin-4-ylamino)prop-1-eny...)
Affinity DataIC50: 190nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202741(N-(4-(4-amino-7-(3-(4-hydroxypiperidin-1-yl)prop-1...)
Affinity DataIC50: 210nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202738(trans-N-(4-(4-amino-7-(3-aminoprop-1-enyl)thieno[3...)
Affinity DataIC50: 230nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202745(4-amino-3-(3-methoxy-4-(1-methyl-1H-indole-2-carbo...)
Affinity DataIC50: 240nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 290nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202754(N-(4-(4-amino-7-(3-(4-methylpiperazin-1-yl)prop-1-...)
Affinity DataIC50: 290nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202744(4-amino-3-(3-methoxy-4-(1-methyl-1H-indole-2-carbo...)
Affinity DataIC50: 380nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 480nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202736(trans-N-(4-(4-amino-7-(3-amino-3-oxoprop-1-enyl)th...)
Affinity DataIC50: 541nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202753(N-(4-(7-(3-acetamidoprop-1-enyl)-4-aminothieno[3,2...)
Affinity DataIC50: 720nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202740(trans-N-(4-(4-amino-7-(3-hydroxyprop-1-enyl)thieno...)
Affinity DataIC50: 770nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202757(N-(4-(4-amino-7-(3-oxo-3-(piperidin-4-ylamino)prop...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202748(N-(4-(4-amino-7-(3-(methylsulfonamido)prop-1-enyl)...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202744(4-amino-3-(3-methoxy-4-(1-methyl-1H-indole-2-carbo...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202746(N-(4-(4-amino-7-(3-(4-methyl-3-oxopiperazin-1-yl)p...)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(N-(4-(4-amino-7-(3-((1r,4r)-4-aminocyclohexylamino...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202733(4-amino-N-(2-(dimethylamino)ethyl)-3-(3-methoxy-4-...)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202736(trans-N-(4-(4-amino-7-(3-amino-3-oxoprop-1-enyl)th...)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202753(N-(4-(7-(3-acetamidoprop-1-enyl)-4-aminothieno[3,2...)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202740(trans-N-(4-(4-amino-7-(3-hydroxyprop-1-enyl)thieno...)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202745(4-amino-3-(3-methoxy-4-(1-methyl-1H-indole-2-carbo...)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202756(N-(4-(4-amino-7-(3-(4-phenylpiperazin-1-yl)prop-1-...)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(N-(4-(4-amino-7-(3-(piperidin-4-ylamino)prop-1-eny...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(N-(4-(4-amino-7-(3-(piperidin-4-ylamino)prop-1-eny...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202748(N-(4-(4-amino-7-(3-(methylsulfonamido)prop-1-enyl)...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202750(cis-N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)t...)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202755(N-(4-(4-amino-7-(3-hydroxypropyl)thieno[3,2-c]pyri...)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202758(N-(4-(4-aminothieno[3,2-c]pyridin-3-yl)-2-methoxyp...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202741(N-(4-(4-amino-7-(3-(4-hydroxypiperidin-1-yl)prop-1...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202754(N-(4-(4-amino-7-(3-(4-methylpiperazin-1-yl)prop-1-...)
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202751(1-(3-(4-amino-3-(3-methoxy-4-(1-methyl-1H-indole-2...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202752(1-(4-amino-3-(3-methoxy-4-(1-methyl-1H-indole-2-ca...)
Affinity DataIC50: 6.85E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202738(trans-N-(4-(4-amino-7-(3-aminoprop-1-enyl)thieno[3...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 9.05E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202743(N-(4-(4,7-diaminothieno[3,2-c]pyridin-3-yl)-2-meth...)
Affinity DataIC50: 9.65E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202741(N-(4-(4-amino-7-(3-(4-hydroxypiperidin-1-yl)prop-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202741(N-(4-(4-amino-7-(3-(4-hydroxypiperidin-1-yl)prop-1...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202735(N-(4-(4-amino-7-(3-((1s,4s)-4-aminocyclohexylamino...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202746(N-(4-(4-amino-7-(3-(4-methyl-3-oxopiperazin-1-yl)p...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thien...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202739(N-(4-(4-amino-7-(3-(piperidin-4-ylamino)prop-1-eny...)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202749(N-(4-(4-amino-7-(1-methylpiperazine-4-carbonyl)thi...)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202737(N-(4-(4-amino-7-(3-((1r,4r)-4-aminocyclohexylamino...)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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