Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50037795
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200886((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of CXCL1-induced human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200881((R)-3-(2-(cyclopropyl(5-methylfuran-2-yl)methylami...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200878((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200885((R)-3-(2-(1-(3-fluorophenyl)propylamino)-3,4-dioxo...)
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200875((R)-3-(2-(1-(benzo[d][1,3]dioxol-5-yl)propylamino)...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200877((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylthioph...)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200886((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-...)
Affinity DataIC50: 5.40nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200887((R)-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propylamino)c...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200888((R)-2-hydroxy-N,N-dimethyl-3-(2-(2-methyl-1-(5-met...)
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200882((R)-3-(2-(2,2-dimethyl-1-(5-methylfuran-2-yl)propy...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50187003(CHEMBL214047 | CHEMBL218964 | 3-(3,4-dioxo-2-(pent...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200876((S)-3-(3,4-dioxo-2-(1-phenylethylamino)cyclobut-1-...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200878((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200888((R)-2-hydroxy-N,N-dimethyl-3-(2-(2-methyl-1-(5-met...)
Affinity DataIC50: 34nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataIC50: 48nMAssay Description:Inhibition of CXCL1-induced human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200881((R)-3-(2-(cyclopropyl(5-methylfuran-2-yl)methylami...)
Affinity DataIC50: 55nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200887((R)-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propylamino)c...)
Affinity DataIC50: 81nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200875((R)-3-(2-(1-(benzo[d][1,3]dioxol-5-yl)propylamino)...)
Affinity DataIC50: 145nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200885((R)-3-(2-(1-(3-fluorophenyl)propylamino)-3,4-dioxo...)
Affinity DataIC50: 197nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200883((S)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataIC50: 234nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200877((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylthioph...)
Affinity DataIC50: 235nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200884(3-(2-(benzylamino)-3,4-dioxocyclobut-1-enylamino)-...)
Affinity DataIC50: 236nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200876((S)-3-(3,4-dioxo-2-(1-phenylethylamino)cyclobut-1-...)
Affinity DataIC50: 244nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataIC50: 254nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200886((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-...)
Affinity DataIC50: 775nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50187003(CHEMBL214047 | CHEMBL218964 | 3-(3,4-dioxo-2-(pent...)
Affinity DataIC50: 910nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200876((S)-3-(3,4-dioxo-2-(1-phenylethylamino)cyclobut-1-...)
Affinity DataIC50: 3.06E+3nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed