Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50018874
TargetLiver carboxylesterase(Pig)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysosomal protective protein(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50199883(cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant CatA using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50199883(cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human leukocyte elastase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysosomal protective protein(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CatA using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLiver carboxylesterase(Pig)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50199883(cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human leukocyte elastase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysosomal protective protein(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant CatA using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLiver carboxylesterase(Pig)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed