Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50018838
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199567(6-methoxy-8-(4-methyl-[1,4]diazepan-1-yl)-4-oxo-1,...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199566(6-methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-1,4-di...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199558(6-fluoro-8-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dih...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199565(6-fluoro-4-methoxy-8-(4-methyl-piperazin-1-yl)-qui...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199559(8-((3R)-(+)-3-dimethylamino-pyrrolidin-1-yl)-6-met...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199564(4-dimethylamino-6-methoxy-8-(4-methyl-piperazin-1-...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199562(8-[ethyl-(1-ethyl-pyrrolidin-3-yl)-amino]-6-methox...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199561(8-[(3-dimethylamino-propyl)-methyl-amino]-6-methox...)
Affinity DataKi:  292nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199563(8-[(2-dimethylamino-ethyl)-methyl-amino]-6-methoxy...)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199557(8-((3S)-3-dimethylamino-pyrrolidin-1-yl)-6-methoxy...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199560(6-methoxy-8-[methyl-(1-methyl-pyrrolidin-3-yl)-ami...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199568(6-methoxy-4-methylamino-8-(4-methyl-piperazin-1-yl...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed