Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 2184
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University

LigandPNGBDBM17847(tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...)
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University

LigandPNGBDBM17849(3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...)
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University

LigandPNGBDBM17850(3-(3-phenylpropanamido)-N-(1,3-thiazol-2-yl)pyridi...)
Affinity DataIC50: 3.50E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University

LigandPNGBDBM17851(3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...)
Affinity DataIC50: 6.40E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Johns Hopkins University

LigandPNGBDBM17847(tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...)
Affinity DataIC50: 3.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University

LigandPNGBDBM17852(3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...)
Affinity DataIC50: 5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Johns Hopkins University

LigandPNGBDBM17849(3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...)
Affinity DataIC50: 5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Johns Hopkins University

LigandPNGBDBM17850(3-(3-phenylpropanamido)-N-(1,3-thiazol-2-yl)pyridi...)
Affinity DataIC50: 5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Johns Hopkins University

LigandPNGBDBM17852(3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...)
Affinity DataIC50: 5.00E+5nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Johns Hopkins University

LigandPNGBDBM17851(3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...)
Affinity DataIC50: 1.00E+6nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed