Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018717
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human CCR4 expressed in CEMS529 cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50: 7nMAssay Description:Inhibition of MDC-induced chemotaxis in L1.2 cells expressing CCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198423((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198433(N4-(2,4-dichlorobenzyl)-N2-(5-(diethylamino)pentan...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(N4-(2,4-dichlorobenzyl)-N2-(4-(diethylamino)pentyl...)
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198425(1-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2...)
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(N4-(2,4-dichlorobenzyl)-N2-(4-(diethylamino)pentyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198427(N4-(2,4-dichlorobenzyl)-N2-(5-(diethylamino)pentan...)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(N4-(2,4-dichlorobenzyl)-N2-(4-(diethylamino)pentyl...)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human CCR4 expressed in CEMS529 cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198430(9-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2...)
Affinity DataIC50: 820nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198436(7-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2...)
Affinity DataIC50: 830nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198428(N6-(2,4-dichlorobenzyl)-N2-(5-(diethylamino)pentan...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198431(N2-(2,4-dichlorobenzyl)-N4-(5-(diethylamino)pentan...)
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198435(N2-(2,4-dichlorobenzyl)-N6-(5-(diethylamino)pentan...)
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198434(N2-(2,4-dichlorobenzyl)-N6-(5-(diethylamino)pentan...)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198424(N2-(2,4-dichlorobenzyl)-N4-(5-(diethylamino)pentan...)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198432(N6-(2,4-dichlorobenzyl)-N2-(5-(diethylamino)pentan...)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(N4-(2,4-dichlorobenzyl)-N2-(4-(diethylamino)pentyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MDC-induced chemotaxis in L1.2 cells expressing CCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed