Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50018714
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198419BDBM50198419(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198395BDBM50198395(1-{[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-...)
Affinity DataKi:  28nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198405BDBM50198405(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  29nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198390BDBM50198390(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  31nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198415BDBM50198415(1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(cycloocte...)
Affinity DataKi:  36nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198389BDBM50198389(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  39nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198418BDBM50198418(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3,5-di...)
Affinity DataKi:  41nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198408BDBM50198408(1-(5-(2-chlorophenyl)thiophen-2-yl)-3-(1-(((1R,5S)...)
Affinity DataKi:  46nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198391BDBM50198391(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3-fluo...)
Affinity DataKi:  47nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198410BDBM50198410(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  70nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198392BDBM50198392(1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-...)
Affinity DataKi:  73nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198414BDBM50198414(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  81nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198386BDBM50198386(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  83nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198404BDBM50198404(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3-(tri...)
Affinity DataKi:  88nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198412BDBM50198412(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3-(tri...)
Affinity DataKi:  104nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198406BDBM50198406(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  107nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198407BDBM50198407(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(5-phen...)
Affinity DataKi:  108nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198394BDBM50198394(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(naphth...)
Affinity DataKi:  110nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198400BDBM50198400(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  141nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198401BDBM50198401(1-(5-bromopyridin-3-yl)-3-(1-(((1R,5S)-6,6-dimethy...)
Affinity DataKi:  171nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198388BDBM50198388(1-(3,5-difluorophenyl)-3-(1-(((1R,5S)-6,6-dimethyl...)
Affinity DataKi:  171nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198411BDBM50198411(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  175nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198399BDBM50198399(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  191nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198417BDBM50198417(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  191nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198398BDBM50198398(1-(3-chlorophenyl)-3-(1-(cyclooctenylmethyl)piperi...)
Affinity DataKi:  201nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198393BDBM50198393(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  229nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198387BDBM50198387(1-(3-acetylphenyl)-3-(1-(((1R,5S)-6,6-dimethylbicy...)
Affinity DataKi:  258nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198396BDBM50198396(1-(1-(2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)...)
Affinity DataKi:  290nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198420BDBM50198420(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(4-phen...)
Affinity DataKi:  306nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198409BDBM50198409(methyl 3-(3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1...)
Affinity DataKi:  376nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Mouse)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198394BDBM50198394(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(naphth...)
Affinity DataKi:  400nMAssay Description:Antagonist activity at mouse CXCR3 by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198422BDBM50198422(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  429nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198394BDBM50198394(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(naphth...)
Affinity DataKi:  600nMAssay Description:Inhibition at human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198402BDBM50198402(1-(3-acetylphenyl)-3-(1-(cyclooctenylmethyl)piperi...)
Affinity DataKi:  637nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198403BDBM50198403(methyl 3-(3-(1-(cyclooctenylmethyl)piperidin-4-yl)...)
Affinity DataKi:  660nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198421BDBM50198421(1-(4-tert-butylphenyl)-3-(1-(cyclooctenylmethyl)pi...)
Affinity DataKi:  1.04E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198416BDBM50198416(1-(naphthalen-2-yl)-3-(1-phenethylpiperidin-4-yl)u...)
Affinity DataKi:  1.30E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198385BDBM50198385(1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...)
Affinity DataKi:  2.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198413BDBM50198413(1-(naphthalen-2-yl)-3-(1-(3-phenylpropyl)piperidin...)
Affinity DataKi:  2.20E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198397BDBM50198397(1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3,5-di...)
Affinity DataKi:  3.40E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed