Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50037868
TargetTyrosine-protein kinase Lck(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 8nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198360(N-(2,6-dimethylphenyl)-5-(3-methoxyphenyl)imidazo[...)
Affinity DataIC50: 11nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198372(N-(2,6-dimethylphenyl)-5-thiophen-2-ylimidazo[1,5-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198370(N-(2,6-dimethyl-phenyl)-5-phenylimidazo[1,5-a]pyra...)
Affinity DataIC50: 13nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198378(N-(2,6-dimethylphenyl)-5-(4-methoxyphenyl)imidazo[...)
Affinity DataIC50: 15nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198361(N-(2,6-dimethylphenyl)-5-[4-(2-pyrrolidin-1-yletho...)
Affinity DataIC50: 15nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198377(N-(2,6-dimethylphenyl)-5-[3-(1-methylpiperidin-3-y...)
Affinity DataIC50: 19nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198365(N-[5-(4-dimethylaminophenyl)imidazo[1,5-a]pyrazin-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 20nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 20nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198354(N-[5-(3,4-dimethoxyphenyl)imidazo[1,5-a]pyrazin-8-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198379(N-(2,6-dimethylphenyl)-5-[4-(2-morpholin-4-ylethox...)
Affinity DataIC50: 37nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198369(N-(5-phenylimidazo[1,5-a]pyrazin-8-yl)-2,4,6-trime...)
Affinity DataIC50: 38nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198366(N-(2,6-dichlorophenyl)-5-phenylimidazo[1,5-a]pyraz...)
Affinity DataIC50: 42nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198357(N-(2,6-dimethylphenyl)-5-(4-fluorophenyl)imidazo[1...)
Affinity DataIC50: 42nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198358(N-(2,6-dimethylphenyl)-5-[5-(4-methylpiperazin-1-y...)
Affinity DataIC50: 52nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198374(4-[8-(2,6-dimethylphenylamino)imidazo[1,5-a]-pyraz...)
Affinity DataIC50: 52nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198376(N-(2,6-dimethylphenyl)-5-[3-(2-pyrrolidin-1-yletho...)
Affinity DataIC50: 55nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198380(N-(2-chloro-6-methylphenyl)-6-(3-methoxyphenyl)imi...)
Affinity DataIC50: 59nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151366((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...)
Affinity DataIC50: 96nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198355(N-(2,6-dimethylphenyl)-5-pyridin-4-ylimidazo[1,5-a...)
Affinity DataIC50: 108nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198363(N-(2-chloro-6-methylphenyl)-6-(4-fluorophenyl)-imi...)
Affinity DataIC50: 145nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198381(N-(2,6-dimethylphenyl)-5-(4-trifluoromethylphenyl)...)
Affinity DataIC50: 235nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198375(4-[8-(2,6-dimethylphenylamino)imidazo[1,5-a]pyrazi...)
Affinity DataIC50: 235nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198356(4-[8-(2,6-dimethylphenylamino)imidazo[1,5-a]-pyraz...)
Affinity DataIC50: 235nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198367(N-[5-(4-methoxyphenyl)imidazo[1,5-a]pyrazin-8-yl]-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370960(CHEMBL541412)
Affinity DataIC50: 305nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198362(N-(2,6-difluorophenyl)-5-phenylimidazo[1,5-a]pyraz...)
Affinity DataIC50: 490nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 530nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198364(N-(2-methoxy-6-methylphenyl)-5-phenylimidazo[1,5-a...)
Affinity DataIC50: 693nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198379(N-(2,6-dimethylphenyl)-5-[4-(2-morpholin-4-ylethox...)
Affinity DataIC50: 700nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198377(N-(2,6-dimethylphenyl)-5-[3-(1-methylpiperidin-3-y...)
Affinity DataIC50: 740nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198358(N-(2,6-dimethylphenyl)-5-[5-(4-methylpiperazin-1-y...)
Affinity DataIC50: 820nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198361(N-(2,6-dimethylphenyl)-5-[4-(2-pyrrolidin-1-yletho...)
Affinity DataIC50: 950nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198376(N-(2,6-dimethylphenyl)-5-[3-(2-pyrrolidin-1-yletho...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370960(CHEMBL541412)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of cSrc in COS7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198382(N-(2,6-dimethylphenyl)imidazo[1,5-a]pyrazin-8-amin...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198384(N-[5-(4-methoxyphenyl)imidazo[1,5-a]pyrazin-8-yl]p...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198371(N-Phenyl-5-phenylimidazo[1,5-a]pyrazin-8-amine | C...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Zap70More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCbeta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198353(CHEMBL534948 | CHEMBL227753 | N-(2,6-dimethylpheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198359(N-methyl-N-phenyl-5-phenylimidazo[1,5-a]pyrazin-8-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of cSrc by coupled spectrophotometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed