Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50038054
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181139((S)-2-amino-2-cyclopropyl-1-((S)-4-(2,5-difluoroph...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181138((S)-2-amino-1-((S)-4-(2,5-difluorophenyl)-2-(3-hyd...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181137((S)-1-((S)-4-(2,5-difluorophenyl)-2-(3-hydroxyphen...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24060((2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluoro...)
Affinity DataIC50: 2nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50181142((S)-4-(2,5-difluorophenyl)-N-(2-hydroxyethyl)-2-(3...)
Affinity DataIC50: 4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24057(CHEMBL203045 | 3-amino-1-[(2S)-4-(2,5-difluorophen...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24062(CHEMBL202788 | 2-hydroxyethyl N-[(2S)-1-[(2S)-4-(2...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24063(CHEMBL382165 | (2S)-2-cyclopropyl-1-[(2S)-4-(2,5-d...)
Affinity DataIC50: 11nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198311((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...)
Affinity DataIC50: 12nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24056((2S)-N-(3-aminopropyl)-4-(2,5-difluorophenyl)-N-me...)
Affinity DataIC50: 16nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198312((S)-1-(3-(2,5-difluorophenyl)-5-phenyl-4,5-dihydro...)
Affinity DataIC50: 26nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24055((2S)-4-(2,5-difluorophenyl)-N-(1-acetylpiperidin-4...)
Affinity DataIC50: 50nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24053(CHEMBL196985 | 3-(2,5-difluorophenyl)-N,N-dimethyl...)
Affinity DataIC50: 84nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198314((3aS,10R)-2-(5-amino-pentyl)-10-(3-hydroxy-phenyl)...)
Affinity DataIC50: 90nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24127(CHEMBL205786 | (4R)-4-(3-hydroxyphenyl)-N,N,7,8-te...)
Affinity DataIC50: 104nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164856(1-(3-(2,5-difluorophenyl)-5-phenyl-4,5-dihydropyra...)
Affinity DataIC50: 250nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198306(N-(3-aminopropyl)-N-((3-benzyl-7-chloro-4-oxo-3,4-...)
Affinity DataIC50: 280nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24127(CHEMBL205786 | (4R)-4-(3-hydroxyphenyl)-N,N,7,8-te...)
Affinity DataIC50: 306nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24066(1-[(5S)-3-(2-chlorophenyl)-5-(3-hydroxyphenyl)-4,5...)
Affinity DataIC50: 450nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24135(CHEMBL438800 | 7-bromo-4-(3-hydroxyphenyl)-N,N-dim...)
Affinity DataIC50: 808nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198302((S)-2-amino-3-(tritylthio)propanoic acid | CHEMBL3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164861(1-[3-(2,5-Difluoro-phenyl)-5-thiophen-2-yl-4,5-dih...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164864(3-(2,5-difluorophenyl)-1-(methylsulfonyl)-5-phenyl...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24110(2-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24067(CHEMBL193686 | 3-(2,5-difluorophenyl)-N-methyl-5-p...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164869(1-[3-(2-Chloro-phenyl)-5-phenyl-4,5-dihydro-pyrazo...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164867(1-(3-(2-fluorophenyl)-5-phenyl-4,5-dihydropyrazol-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198310(ethanesulfonate8-[3-(2-chloro-phenothiazin-10-yl)-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198304(N-ethyl-2-(4-(3-(2-(trifluoromethyl)-10H-phenothia...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24105(CHEMBL208145 | 7,8-dimethyl-4-phenyl-1,2,3,4-tetra...)
Affinity DataIC50: 8.23E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198308((R)-2-methyl-4-phenyl-1,2,3,4,8,9-hexahydrofuro[2,...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164866(1-(3-(3-chlorophenyl)-5-phenyl-4,5-dihydropyrazol-...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198309(Monastrol | (S)-4-(3-Hydroxy-phenyl)-6-methyl-2-th...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198303((1S,2S,5S,9R,10R,11R,14S)-7-(2-hydroxypropan-2-yl)...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198305(1,4,5,6,7,16,17,18,19,19,20,20-dodecachloro-12-sul...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24107(CHEMBL207973 | 2-ethyl-7,8-dimethyl-4-phenyl-1,2,3...)
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198313(2,6-dichloro-4-[2-(2-chloro-3-hydroxyphenyl)-1,2-b...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198307(2-(2-(8-hydroxyquinolin-2-yl)disulfanyl)quinolin-8...)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed