Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 1542
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 350nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 5.60E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.24E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.35E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.50E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.60E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 2.00E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 2.20E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 2.60E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 2.60E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 4.20E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 4.40E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 5.10E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 5.60E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 6.80E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 6.90E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 7.00E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 7.70E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palacky University

LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 7.70E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palacky University

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 8.20E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12025(4-[(E)-2-(2-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 8.80E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palacky University

LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palacky University

LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palacky University

LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12026(4-[(E)-2-(3-nitrophenyl)diazen-1-yl]-1H-pyrazole-3...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12024(4-[(E)-2-phenyldiazen-1-yl]-1H-pyrazole-3,5-diamin...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12029({2-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed