Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 2128
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17204(2-[(2,6-dichlorophenyl)formamido]-3-(2-phenylquino...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17211(2-[(2,6-dichlorophenyl)formamido]-3-[2-(1,3-thiazo...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17208(2-[(2,6-dichlorophenyl)formamido]-3-[2-(4-methanes...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17217(2-[(2-chloro-4-methanesulfonylphenyl)formamido]-3-...)
Affinity DataIC50: 3.5nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17216(2-[(2-chloro-6-methylphenyl)formamido]-3-[2-(2,6-d...)
Affinity DataIC50: 3.90nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17203(3-[2-(2-chloro-6-nitrophenyl)quinolin-6-yl]-2-[(2,...)
Affinity DataIC50: 6.5nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17220(2-{[1-(4-chlorophenyl)cyclopentyl]formamido}-3-[2-...)
Affinity DataIC50: 6.60nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17207(2-[(2,6-dichlorophenyl)formamido]-3-[2-(2-methoxyn...)
Affinity DataIC50: 7.30nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17197(2-[(2,6-dichlorophenyl)formamido]-3-[2-(2,6-dichlo...)
Affinity DataIC50: 7.80nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17218(2-[(2,4-dichloro-6-methylpyridin-3-yl)formamido]-3...)
Affinity DataIC50: 7.90nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17210(2-[(2,6-dichlorophenyl)formamido]-3-[2-(2,6-dichlo...)
Affinity DataIC50: 8.60nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17221(2-{[(2S)-1-benzyl-5-oxopyrrolidin-2-yl]formamido}-...)
Affinity DataIC50: 15.3nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17198(2-[(2,6-dichlorophenyl)formamido]-3-[2-(2,6-dimeth...)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17202(3-[2-(2-chloro-6-fluorophenyl)quinolin-6-yl]-2-[(2...)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17214(3-[2-(2,6-dichlorophenyl)quinolin-6-yl]-2-[(2,6-di...)
Affinity DataIC50: 37.2nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17213(3-[2-(2,6-dichlorophenyl)quinolin-6-yl]-2-[(2,6-di...)
Affinity DataIC50: 53.7nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17206(2-[(2,6-dichlorophenyl)formamido]-3-{2-[2-(trifluo...)
Affinity DataIC50: 92nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17201(2-[(2,6-dichlorophenyl)formamido]-3-[2-(2,6-dimeth...)
Affinity DataIC50: 102nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17205(3-[2-(2-bromophenyl)quinolin-6-yl]-2-[(2,6-dichlor...)
Affinity DataIC50: 154nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17212(3-{2-[2-chloro-5-(trifluoromethyl)phenyl]quinolin-...)
Affinity DataIC50: 209nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17200(2-[(2,6-dichlorophenyl)formamido]-3-[2-(2,6-difluo...)
Affinity DataIC50: 372nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17209(2-[(2,6-dichlorophenyl)formamido]-3-[2-(pyridin-4-...)
Affinity DataIC50: 381nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17215(3-[2-(2,6-dichlorophenyl)quinolin-6-yl]-2-[(2,6-di...)
Affinity DataIC50: 435nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17199(2-[(2,6-dichlorophenyl)formamido]-3-[2-(2,4-dichlo...)
Affinity DataIC50: 748nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Ucb Pharma

LigandPNGBDBM17219(3-[2-(2,6-dichlorophenyl)quinolin-6-yl]-2-(phenylf...)
Affinity DataIC50: 5.64E+3nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed