Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 2396
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM20001(2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 1.90nM EC50:  33nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 2.10nM EC50:  71nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19999(2-(4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50: 5nM EC50:  143nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM20002(CHEMBL216645 | 2-{4-[({3-[3-benzyl-8-(trifluoromet...)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM20001(2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 7.60nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 9.5nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 10nM EC50:  16nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataIC50: 12nM EC50:  410nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19999(2-(4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50: 16.5nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM20002(CHEMBL216645 | 2-{4-[({3-[3-benzyl-8-(trifluoromet...)
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19995(4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]p...)
Affinity DataIC50: 67nM EC50:  186nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19994(3-benzoyl-4-phenyl-8-(trifluoromethyl)quinoline | ...)
Affinity DataIC50: 107nM EC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM20003(2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 115nM EC50:  374nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19995(4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]p...)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19994(3-benzoyl-4-phenyl-8-(trifluoromethyl)quinoline | ...)
Affinity DataIC50: 260nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM20003(2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 274nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19998(4-{4-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]p...)
Affinity DataIC50: 723nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19996(methyl 4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin...)
Affinity DataIC50: 1.00E+3nM EC50:  296nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19996(methyl 4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin...)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19997(3-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]p...)
Affinity DataIC50: 1.03E+3nM EC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19997(3-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]p...)
Affinity DataIC50: 1.87E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19998(4-{4-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]p...)
Affinity DataIC50: 2.74E+3nM EC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed